Results 221 to 230 of about 5,041,695 (380)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Genetic Population Structure of the Italian Wall Lizards <i>Podarcis siculus</i> (Squamata: Lacertidae): Insight From Nuclear DNA Markers. [PDF]

Ecol Evol
Senczuk G, Ripa C, Colangelo P, Castiglia R.   +3 more
europepmc   +1 more source

Mitochondrial double-stranded RNA triggers induction of the antiviral DNA deaminase APOBEC3A and nuclear DNA damage. [PDF]

J Biol Chem, 2023
Wick C, Moghadasi SA, Becker JT, Fanunza E, Oh S, Bournique E, Buisson R, Harris RS.   +7 more
europepmc   +1 more source

Combined analysis of nuclear morphometry and DNA cytofluorometry on thyroid tumors.

, 1990
Sin-ichi MURATA, Hirosumi Itoi, Yoji Urata, Yasunari Tsuchihashi, Fumio Matsuzuka, Tsukasa Ashihara   +5 more
openalex   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

A denaturation-free protocol for in situ visualization of short nuclear DNA sequences using padlock probes with rolling-circle amplification. [PDF]

PLoS One
Ikebuchi R, Xi L, Bouri D, Svintytska V, Davies H, Olszewski P, Bruhn-Olszewska B, Dumanski JP, Landegren U.   +8 more
europepmc   +1 more source

STUDIES ON THE CITRUS GENERIC POLYEMBRYONY IN REATION TO BREEDING. : 1. Labeling of the Nuclear DNA of Pollen with 3<SUP>H</SUP> and <14><SUP>C</SUP>.

, 1969
Katsumi Syakudou, H. Yamagata, Hiroshi Watanabe   +2 more
openalex   +2 more sources

Mitochondrial reactive oxygen species are scavenged by Cockayne syndrome B protein in human fibroblasts without nuclear DNA damage

Proceedings of the National Academy of Sciences of the United States of America, 2014
J. Cleaver, A. M. Brennan-Minnella, R. Swanson, K. Fong, Junjie Chen, K. Chou, Yih-wen Chen, I. Revet, V. Bezrookove   +8 more
semanticscholar   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Mitochondrial and Nuclear DNA Analyses of <i>Rhipicephalus microplus</i> from Mizoram, Northeast India: Insights into Genetic Diversity and Endosymbiont. [PDF]

Genes (Basel)
Lalawmpuii K, Jacob SS, Tolenkhomba TC, Behera P, Lalmuanpuia J, Lalremsanga HT, Lalrintluanga K, Lalchhandama C, Biakzuala L, Lalrinkima H.   +9 more
europepmc   +1 more source