Results 331 to 340 of about 5,041,695 (380)
Some of the next articles are maybe not open access.
MNGIE: from nuclear DNA to mitochondrial DNA
Neuromuscular Disorders, 2001Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a unique autosomal recessive disorder with mitochondrial DNA alterations. The disease is characterized clinically by ptosis, progressive external ophthalmoparesis, gastrointestinal dysmotility, cachexia, peripheral neuropathy, and leukoencephalopathy.
I, Nishino, A, Spinazzola, M, Hirano
openaire +2 more sources
DNA replication and nuclear architecture
Journal of Cellular Biochemistry, 2002AbstractThe model of in situ DNA replication provided by immunofluorescence and confocal imaging is compared with observations obtained by electron microscopic studies. Discrepancies between both types of observations call into question the replication focus as a persistent nuclear structure and as a replication entity where DNA replication takes place.
Françoise, Jaunin, Stanislav, Fakan
openaire +2 more sources
Nuclear compartmentalization of DNA repair
Current Opinion in Genetics & Development, 2016The continuous threats on genome integrity by endogenous and exogenous sources have rendered cells competent to overcome these challenges by activating DNA repair pathways. A complex network of proteins and their modifications participate in orchestrated signaling cascades, which are induced in response to DNA damage and may determine the choice of ...
Alkmini, Kalousi, Evi, Soutoglou
openaire +2 more sources
Nuclear DNA content in Gastrotricha
Experientia, 1995A cytofluorometric evaluation of nuclear DNA content was carried out on fifteen species of Gastrotricha. Genome size, ranging from 0.05 to 0.63 pg, appears uniform in this group and rather low compared to values found in other lower Metazoa. Differences in DNA content between the two orders of the phylum, Macrodasyida and Chaetonotida, which differ ...
BALSAMO M, MANICARDI, Gian Carlo
openaire +3 more sources
Nuclear satellite DNAs of yeast
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1972High molecular weight DNA isolated from yeast nuclei has been fractionated in Ag+-Cs2SO4 and Hg2+-Cs2SO4 density gradients. Centrifugation in Ag+-Cs2SO4 gradients resulted in the appearance of a satellite band on the heavy side of the gradients. This satellite DNA, which accounts for 3–5 % of the total DNA, does not code for either 26-S, 17-S and 5 ...
J, Retèl, R J, Planta
openaire +2 more sources
1998
Since its introduction in 1985, the polymerase chain reaction (PCR) (1) has profoundly affected the way in which molecular studies are conducted. Olsen et al. (2) first proposed that short single copy DNA sequences could be amplified by PCR from cloned DNA using specific primers.
Joanne Russell +2 more
openaire +1 more source
Since its introduction in 1985, the polymerase chain reaction (PCR) (1) has profoundly affected the way in which molecular studies are conducted. Olsen et al. (2) first proposed that short single copy DNA sequences could be amplified by PCR from cloned DNA using specific primers.
Joanne Russell +2 more
openaire +1 more source
Nuclear DNA amounts in crustacea
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1974Abstract 1. 1. Nuclear DNA amounts of thirty-eight species of crustaceans, belonging to three subclasses and seven orders, were determined by cytophotometry or by fluorometric assay. 2. 2. DNA contents vary over a wide range (0·7–22·6 pg haploid). A modal value of about 2·5 pg is typical for many groups. 3. 3. The extreme values are found
E L, Rheinsmith +2 more
openaire +2 more sources
DNA synthesis in nuclear protrusions
Experimental Cell Research, 1971Abstract The broken ends of mitotic bridges persisting into interphase often form nuclear protrusions in HeLa cells: DNA synthesis localised at the protrusions may take place in S or in G2 as late as prophase or thereabouts. These nuclear sites are found to be associated with a ring chromosome in a number of cases.
openaire +2 more sources
Nuclear matrix-associated DNA methylase
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1985Previous procedures for the extraction of DNA methylase (EC 2.1.1.37) from nuclei of mouse ascites cells have involved the use of buffers containing 0.2M NaCl. Whilst such 'soluble' methylase accounts for the bulk (70-80%) of DNA methylase activity a further portion of activity is detectable in a 'bound' form firmly associated with 2 M NaCl-resistant ...
R H, Burdon, M, Qureshi, R L, Adams
openaire +2 more sources