Results 111 to 120 of about 7,608,807 (307)

Geographies of Nuclear Energy. An Introduction.

Historical Social Research
Nuclear energy has long attracted the attention of scholars in the humanities and social sciences. With this HSR Special Issue, we would like to push the scholarly frontier by highlighting the geographies of nuclear energy in the past and present. Nuclear energy is inherently interwoven with geography.
Gutting, Alicia, Högselius, Per, Meyer, Teva, Mbah, Melanie   +3 more
openaire   +3 more sources

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Nuclear Energy for Variable Electricity and Liquid Fuels Production: Integrating Nuclear with Renewables, Fossil Fuels, and Biomass for a Low- Carbon World

, 2011
The world faces two energy challenges: (1) the national security and economic challenge of dependence on foreign oil and (2) the need to reduce carbon dioxide emissions from the burning of fossil fuels to avoid climate change.
Forsberg, Charles W.
core  

Constitutional Discussions on Nuclear Energy in Germany

This book analyses the German constitutional system's responses towards nuclear energy. Robert Rybski begins with a presentation of energy security as a constitutional value and explores how it connects with nuclear energy.
Rybski, Robert
core   +1 more source

U.S. Department of Energy Strategic Plan

, 2012
The mission of the Department of Energy is to ensure America's security and prosperity by addressing its energy, environmental, and nuclear challenges through transformative science and technology solutions.
United States. Department of Energy.
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Harnessing Nuclear Energy to Gold Nanoparticles for the Concurrent Chemoradiotherapy of Glioblastoma. [PDF]

Nanomaterials (Basel), 2023
Li JP, Kuo YC, Liao WN, Yang YT, Chen SY, Chien YT, Wu KH, Wang MY, Chou FI, Yang MH, Hueng DY, Yang CS, Chen JK.   +12 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source