Results 91 to 100 of about 9,774,890 (311)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Study of (n,2n) reaction cross section of fission product based on neural network and decision tree models [PDF]

EPJ Web of Conferences
The neutron induced nuclear reaction cross sections of fission products are related with the neutron fiux and the reactor burnup, which are important for the accurate of nuclear engineering design. To predict the (n,2n) reaction cross section, especially
Sun Xiaodong, Wei Zihao, Wang Duan, Xu Ruirui, Tian Yuan, Tao Xi, Zhang Yingxun, Zhang Yue, Zhang Zhi, Ge Zhigang, Wang Jimin, Xia Houqiong, Shu Nengchuan   +12 more
doaj   +1 more source

The Effect of Renewable and Nuclear Energy Consumption on Decoupling Economic Growth from CO2 Emissions in Spain

, 2020
This study examines the relationship between renewable and nuclear energy consumption, carbon dioxide emissions and economic growth by using the Granger causality and non-linear impulse response function in a business cycle in Spain.
M. Piłatowska, Andrzej Geise, A. Włodarczyk   +2 more
semanticscholar   +1 more source

Public opinion on nuclear energy and nuclear weapons: The attitudinal nexus in the United States

Energy Research & Social Science, 2020
Does a lack of enthusiasm for nuclear energy among the US public relate to connections with nuclear weapons? The United States is projected to decline as the global leader in nuclear power production due to stagnation in the industry.
J. Baron, Stephen Herzog
semanticscholar   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Validation of ENDF/B-VIII.0 and NCrystal thermal scattering laws for graphite in criticality safety analysis using OpenMC

Nuclear Analysis
Accurate prediction of criticality in nuclear systems relies on high-fidelity nuclear data, particularly for thermal neutron scattering in moderating and reflecting materials.
Abdelhamid Jalil, Houda Abbassi, Mohamed El oulki, Mohammed Hassouni   +3 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Use of 2-color flow cytometry to assess radiation-induced genotoxic damage on CHO-KI cells

Brazilian Journal of Radiation Sciences, 2019
The micronucleus assay is an important technique used to evaluate genotoxic damage of chemical or physical agents (as ionizing radiations) on cells, based on quantification of cells bearing micronuclei, which are fragments derived from damage (breakage ...
Luma Ramirez de Carvalho, Letícia Bonfim, Daniel Perez Vieira   +2 more
doaj   +1 more source