Results 81 to 90 of about 1,459,761 (217)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Irradiation of intraerythrocytic Plasmodium berghei with a fractionated dose of gamma rays does not effectively reduce the infectivity in mice Mus musculus

Aceh Journal of Animal Science, 2019
Malaria infection kills more than one million human every year, mainly under-5-year-old children, including in South East Asian nations. Gamma radiation given at a single dose is commonly used to create the attenuated Plasmodium parasites to get vaccine ...
Mukh Syaifudin, Siti Nurhayati, Darlina Darlina, Yanti Lusiyanti, Teja Kisnanto   +4 more
doaj   +1 more source

Rescattering effects in hadron-nucleus and heavy-ion collisions

, 2005
We review the extension of the factorization formalism of perturbative QCD to {\it coherent} soft rescattering associated with hard scattering in high energy nuclear collisions.
0207, 441, 452, 67, 91, Baier, Collaboration, Collaboration, Collaboration, Collaborations, Collins, Gribov, Guo, Guo, Guo, Gyulassy, Gyulassy, J. Qiu, Jaffe, Lin, Luo, Luo, Mueller, Qiu, Qiu, Qiu, Qiu, Qiu, Qiu, Qiu, Rapp, Wilson, Wong, Zakharov, Zhu   +34 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Study of (n,2n) reaction cross section of fission product based on neural network and decision tree models [PDF]

EPJ Web of Conferences
The neutron induced nuclear reaction cross sections of fission products are related with the neutron fiux and the reactor burnup, which are important for the accurate of nuclear engineering design. To predict the (n,2n) reaction cross section, especially
Sun Xiaodong, Wei Zihao, Wang Duan, Xu Ruirui, Tian Yuan, Tao Xi, Zhang Yingxun, Zhang Yue, Zhang Zhi, Ge Zhigang, Wang Jimin, Xia Houqiong, Shu Nengchuan   +12 more
doaj   +1 more source

Chiral Dynamics in Nuclear Systems

, 2003
A survey is given on selected topics concerning the role of spontaneous chiral symmetry breaking in low-energy QCD, and its dynamical implications for nuclear systems. This includes aspects of chiral thermodynamics (the temperature and density dependence
Weise, Wolfram
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Effective theory for low-energy nuclear energy density functionals

, 2012
We introduce a new class of effective interactions to be used within the energy-density-functional approaches. They are based on regularized zero-range interactions and constitute a consistent application of the effective-theory methodology to low-energy
Bennaceur, K., Dobaczewski, J., Raimondi, F.   +2 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source