Results 121 to 130 of about 9,792,066 (384)

Use of 2-color flow cytometry to assess radiation-induced genotoxic damage on CHO-KI cells

Brazilian Journal of Radiation Sciences, 2019
The micronucleus assay is an important technique used to evaluate genotoxic damage of chemical or physical agents (as ionizing radiations) on cells, based on quantification of cells bearing micronuclei, which are fragments derived from damage (breakage ...
Luma Ramirez de Carvalho, Letícia Bonfim, Daniel Perez Vieira   +2 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Effective theory for low-energy nuclear energy density functionals

, 2012
We introduce a new class of effective interactions to be used within the energy-density-functional approaches. They are based on regularized zero-range interactions and constitute a consistent application of the effective-theory methodology to low-energy
Bennaceur, K., Dobaczewski, J., Raimondi, F.   +2 more
core   +3 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Anion-adaptive crystalline cationic material for 99TcO4 − trapping

Nature Communications, 2019
Efficient anion recognition and trapping is of great significance for anion-specific separation processes but the design of an anion-adaptive sorbents remains a challenge. Here the authors use a cucurbit[8]uril based soft cationic supramolecular material
Lei Mei, Fei-ze Li, Jian-hui Lan, Cong-zhi Wang, Chao Xu, Hao Deng, Qun-yan Wu, Kong-qiu Hu, Lin Wang, Zhi-fang Chai, Jing Chen, John K. Gibson, Wei-qun Shi   +12 more
doaj   +1 more source

Transverse emission of isospin ratios as a probe of high-density symmetry energy in isotopic nuclear reactions

, 2011
Transverse emission of preequilibrium nucleons, light clusters (complex particles) and charged pions from the isotopic $^{112,124}$Sn+$^{112,124}$Sn reactions at a beam energy of 400\emph{A} MeV, to extract the high-density behavior of nuclear symmetry ...
Baran, Di Toro, Famiano, Feng, Feng, Feng, Feng, Feng, Feng, Feng, Feng, Ferini, Giordano, Holzmanna, Holzmanna, Kumar, Li, Li, Li, Russotto, Steiner, ter Haar, Tsang, Xiao, Yong, Zhao-Qing Feng   +25 more
core   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Bertini intra-nuclear cascade implementation in Geant4

, 2003
We present here a intra-nuclear cascade model implemented in Geant4 5.0. The cascade model is based on re-engineering of INUCL code. Models included are Bertini intra-nuclear cascade model with exitons, pre-equilibrium model, nucleus explosion model ...
Heikkinen, Aatos, Stepanov, Nikita, Wellisch, J. P.   +2 more
core  

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Harnessing Nuclear Energy to Gold Nanoparticles for the Concurrent Chemoradiotherapy of Glioblastoma. [PDF]

Nanomaterials (Basel), 2023
Li JP, Kuo YC, Liao WN, Yang YT, Chen SY, Chien YT, Wu KH, Wang MY, Chou FI, Yang MH, Hueng DY, Yang CS, Chen JK.   +12 more
europepmc   +1 more source