Results 61 to 70 of about 9,792,066 (384)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

A PROPOSAL OF PROCESS VALIDATION IN THE IMPLEMENTATION OF GOOD MANUFACTURING PRACTICES IN BRACHYTHERAPY SOURCES PRODUCTION

open access: yesBrazilian Journal of Radiation Sciences, 2021
New laboratories for brachytherapy sources production are being implemented in our facility at IPEN, in São Paulo. A great challenge implementing a production laboratory is to comply with the Good Manufacturing Practices (GMPs), which involves process ...
Tatyana Spinosa Baptista   +5 more
doaj   +1 more source

Ionization Yield from Nuclear Recoils in Liquid-Xenon Dark Matter Detection [PDF]

open access: yes, 2013
The ionization yield in the two-phase liquid xenon dark-matter detector has been studied in keV nuclear-recoil energy region. The newly-obtained nuclear quenching as well as the recently-measured average energy required to produce an electron-ion pair ...
Ji, Xiangdong, Mu, Wei
core  

Nuclear structure far from stability

open access: yes, 2004
Modern nuclear structure theory is rapidly evolving towards regions of exotic short-lived nuclei far from stability, nuclear astrophysics applications, and bridging the gap between low-energy QCD and the phenomenology of finite nuclei.
Bender   +105 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Economics of nuclear energy [PDF]

open access: yes, 2012
While few people now believe that nuclear power would provide ‘power too cheap to meter’, there is still a common perception that nuclear power is a cheap source of electricity.
Thomas, Stephen
core  

Effect of symmetry energy on two-nucleon correlation functions in heavy-ion collisions induced by neutron-rich nuclei [PDF]

open access: yes, 2003
Using an isospin-dependent transport model, we study the effects of nuclear symmetry energy on two-nucleon correlation functions in heavy ion collisions induced by neutron-rich nuclei.
B. A. Li   +7 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Calibration coefficients of epitaxial diodes used in diagnostic radiology and computed tomography beams

open access: yesBrazilian Journal of Radiation Sciences
The assessment of the calibration coefficients of an epitaxial diode, previously characterized for diagnostic radiology (RQR qualities) and computed tomography (RQT qualities) dosimetry, is reported in this work. The diode, with an n-type epitaxial layer
Josemary A. C. Gonçalves   +3 more
doaj   +1 more source

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