Results 201 to 210 of about 4,877,486 (368)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Comparisons of Nuclear Characteristics between Circular Core Cell and Rectangular Core Cell as Material Engineering Test Reactor

, 1964
Kazuo Nishimura, Akikazu IWASE, Toshitake Takahashi, Hifumi YANAGISAWA, Yoshio FUKUMITSU, Hiroyuki Matsunobu, Toru Maejima   +6 more
openalex   +2 more sources

Building confidence in models for complex barrier systems for radionuclides. [PDF]

Proc Natl Acad Sci U S A
Sarsenbayev D, Tournassat C, Steefel CI, Wainwright HM.   +3 more
europepmc   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

Bibliography of Connecticut Advanced Nuclear Engineering Laboratory reports

, 1965

openalex   +2 more sources

Enhancement of quantum coherence in solid-state qubits via interface engineering. [PDF]

Nat Commun
Lo WK, Zhang Y, Chow HY, Wu J, Leung MY, Ho KO, Du X, Chen Y, Shen Y, Pan D, Yang S.   +10 more
europepmc   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

NUCLEAR TECHNOLOGY BRANCHES QUARTERLY REPORT, JULY 1-SEPTEMBER 30, 1964. Formerly--Materials Testing Reactor-Engineering Test Reactor Technical Branches

, 1965
Not Given Author
openalex   +2 more sources

Microtopography-induced changes in cell nucleus morphology enhance bone regeneration by modulating the cellular secretome. [PDF]

Nat Commun
Wang X, Li Y, Lin Z, Pla I, Gajjela R, Mattamana BB, Joshi M, Liu Y, Wang H, Zun AB, Wang H, Wai CM, Agrawal V, Dunton CL, Duan C, Jiang B, Backman V, He TC, Reid RR, Luo Y, Ameer GA.   +20 more
europepmc   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source