Results 101 to 110 of about 407,559 (210)

Nuclear envelope impairment is facilitated by the herpes simplex virus 1 Us3 kinase [version 1; peer review: 2 approved]

open access: yesF1000Research, 2019
Background: Capsids of herpes simplex virus 1 (HSV-1) are assembled in the nucleus, translocated either to the perinuclear space by budding at the inner nuclear membrane acquiring tegument and envelope, or released to the cytosol in a “naked” state via ...
Peter Wild   +7 more
doaj   +1 more source

Nuclear envelope morphology change upon repetitive treatment with modified antisense oligonucleotides targeting Hutchinson-Gilford Progeria Syndrome

open access: yesBiochemistry and Biophysics Reports, 2023
We present the influence of treating progeroid fibroblasts with two modified antisense oligonucleotides (ONs) on the nuclear envelope. Two modified ONs were designed to block ribosome binding during translation and spliceosome binding at the cryptic ...
Asmaa Abdelrahman   +3 more
doaj  

Samp1 Mislocalization in Emery-Dreifuss Muscular Dystrophy

open access: yesCells, 2018
LMNA linked-Emery-Dreifuss muscular dystrophy (EDMD2) is a rare disease characterized by muscle weakness, muscle wasting, and cardiomyopathy with conduction defects.
Elisabetta Mattioli   +5 more
doaj   +1 more source

Calcium signals can freely cross the nuclear envelope in hippocampal neurons: somatic calcium increases generate nuclear calcium transients

open access: yesBMC Neuroscience, 2007
Background In hippocampal neurons, nuclear calcium signaling is important for learning- and neuronal survival-associated gene expression. However, it is unknown whether calcium signals generated by neuronal activity at the cell membrane and propagated to
Bading Hilmar, Eder Anja
doaj   +1 more source

Why Do Stars Turn Red? I. Post-Main-Sequence Expansion Mechanism [PDF]

open access: yesarXiv
We revisit the long-standing question: Why do post-main-sequence stars evolve into red giants (RGs) or red supergiants (RSGs)? Using the 1D stellar evolution code MESA, we perform numerical experiments to compare stellar models that successfully transition into RGs/RSGs with those that remain blue.
arxiv  

SOME OBSERVATIONS ON THE NUCLEAR ENVELOPE [PDF]

open access: bronze, 1960
W. Gordon Whaley   +2 more
openalex   +1 more source

The LINC complex component Sun4 plays a crucial role in sperm head formation and fertility

open access: yesBiology Open, 2015
LINC complexes are evolutionarily conserved nuclear envelope bridges, physically connecting the nucleus to the peripheral cytoskeleton. They are pivotal for dynamic cellular and developmental processes, like nuclear migration, anchoring and positioning ...
Elisabeth Pasch   +4 more
doaj   +1 more source

Forming a clumpy circumstellar material in energetic pre-supernova activity [PDF]

open access: yesarXiv
We demonstrate by three-dimensional hydrodynamical simulations of energy deposition into the envelope of a red supergiant (RSG) model the inflation of a Rayleigh-Taylor unstable envelope that forms a compact clumpy circumstellar material (CSM).
arxiv  

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