Results 91 to 100 of about 149,980 (205)
The nuclear membrane proteome: extending the envelope [PDF]
, 2005 The marriage of proteomics with cell biology has produced extensive inventories of the proteins that inhabit several subcellular organelles. Recent proteomic analysis has identified many new putative transmembrane proteins in the nuclear envelope, and ...
Gerace, Larry, Schirmer, Eric C
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Dynamics and Structure-Function Relationships of the Lamin B Receptor (LBR).
PLoS ONE, 2017 The lamin B receptor (LBR) is a multi-spanning membrane protein of the inner nuclear membrane that is often employed as a "reporter" of nuclear envelope dynamics. We show here that the diffusional mobility of full-length LBR exhibits significant regional
Ioannis Giannios +2 more
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The nuclear envelope as a chromatin organizer [PDF]
, 2011 In the past 15 years our perception of nuclear envelope function has evolved perhaps nearly as much as the nuclear envelope itself evolved in the last 3 billion years.
Robson, M.I. +8 more
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Nuclear Envelope in Nuclear Positioning and Cell Migration [PDF]
, 2014 Hauling and anchoring the nucleus within immobile or motile cells, tissues, and/or syncytia represents a major challenge. In the past 15 years, Linkers of the Nucleoskeleton to the Cytoskeleton (LINC complexes) have emerged as evolutionary-conserved molecular devices that span the nuclear envelope and provide interacting interfaces for cytoskeletal ...
David, Razafsky +2 more
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Nuclear envelope influences on cell-cycle progression [PDF]
, 2011 The nuclear envelope is a complex double membrane system that serves as a dynamic interface between the nuclear and cytoplasmic compartments. Among its many roles is to provide an anchor for gene regulatory proteins on its nucleoplasmic surface and for ...
Korfali, Nadia +5 more
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The role of A-Type lamins and LAP2a in cellular ageing of human fibroblasts in vitro [PDF]
, 2005 Mutations in LMNA gene have been linked to a number of age-related tissue-specific diseases and premature ageing syndromes termed laminopathies. The finding that A- type lamins affect longevity and maintenance of a number of somatic tissues makes them ...
PekovicÌ, Vanja, Peković, Vanja
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Nuclear Membrane: Nuclear Envelope PORosity in Fission Yeast Meiosis [PDF]
, 2010 SummaryThe fission yeast Schizosaccharomyces pombe undergoes closed mitosis but ‘virtual nuclear envelope breakdown’ at anaphase of meiosis II, in which the nuclear envelope is structurally closed but functionally ...
Shelley Sazer, Sazer, Shelley
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Internal iamin structures within G1 nuclei of human dermal fibroblasts [PDF]
, 1993 The nuclear lamina is a mesh-like network of fibres subjacent to the inner nuclear membrane that is believed to be involved in the specific spatial reorganisation of chromatin after mitosis.
Kill, IR +3 more
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An investigation of emerin and nuclear lamins: : Interactions, distribution, and role in cell cycle regulation, in cells derived from EDMD patients. [PDF]
, 2002 Emery Dreifuss muscular dystrophy (EDMD) is caused by mutations either in the gene encoding emerin or in the gene encoding A-type lamins (lamins A and C).
Maria, Choleza
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