Results 1 to 10 of about 5,180,956 (219)

LINC complex protein nesprin-2 has pro-apoptotic activity via Bcl-2 family proteins. [PDF]

Cell Death Discov
Lindenboim L, Zohar H, Gundersen GG, Worman HJ, Stein R.   +4 more
europepmc   +1 more source

Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins. [PDF]

Cell Death Discov, 2020
Lindenboim L, Grozki D, Amsalem-Zafran AR, Peña-Blanco A, Gundersen GG, Borner C, Hodzic D, Garcia-Sáez AJ, Worman HJ, Stein R.   +9 more
europepmc   +1 more source

Recruitment of BAF to the nuclear envelope couples the LINC complex to endoreplication.

Development, 2020
Unnikannan CP, Reuveny A, Grunberg D, Volk T.   +3 more
europepmc   +1 more source

In-cell structure of a LINC complex reveals the molecular basis for membrane remodelling and head-to-tail coupling in sperm cells

Dendooven T, Ebrahimi M, dos Santos A, Dhondt W, Knowles O, Hale T, Burt A, Mehdipour AR, Allegretti M.   +8 more
europepmc   +1 more source

Cell stretchers and the LINC complex in mechanotransduction [PDF]

Archives of Biochemistry and Biophysics, 2021
How cells respond to mechanical forces from the surrounding environment is critical for cell survival and function. The LINC complex is a central component in the mechanotransduction pathway that transmits mechanical information from the cell surface to the nucleus. Through LINC complex functionality, the nucleus is able to respond to mechanical stress
Henning Horn, Noor Al-Maslamani, Abdulghani Khilan   +2 more
exaly   +4 more sources

The assembly of a noncanonical LINC complex in Saccharomyces cerevisiae

Current Genetics, 2021
The linker of nucleoskeleton and cytoskeleton (LINC) complex is a protein complex across the nuclear envelope and has maintained its general assembly mode throughout evolution. SUN and KASH proteins, which are the major components of LINC complex, interact with each other in the nuclear lumen to transmit forces across the nuclear envelope and have ...
Yang Wang, Jinbo Fan, Zhuo Sun
exaly   +3 more sources

LINC Complex Proteins in Development and Disease

Current Topics in Developmental Biology, 2014
The LINC complex spans the nuclear envelope and plays critical roles in coordinating nuclear and cytoplasmic activities and in organizing nuclear and cytoskeletal features. LINC complexes are assembled from KASH and SUN-domain proteins, which interact in the nuclear envelope and form a physical link between the cytoskeleton and the nuclear interior.
Henning Horn
exaly   +3 more sources

Dynamic regulation of LINC complex composition and function across tissues and contexts

FEBS Letters, 2023
Megan King
exaly  

Signal Transduction across the Nuclear Envelope: Role of the LINC Complex in Bidirectional Signaling

Cells, 2019
Miki Matsumura
exaly  

Conserved SUN-KASH Interfaces Mediate LINC Complex-Dependent Nuclear Movement and Positioning

Current Biology, 2018
Mohammad R K Mofrad, Daniel Starr, Gw Gant Luxton   +2 more
exaly