Results 1 to 10 of about 4,811 (148)
SV40 exploits the Nesprin-2-SUN1-KPNA4 axis for stepwise targeting and entry into the host nucleus to promote infection. [PDF]
PLoS PathogensMany DNA viruses including polyomaviruses (PyVs) enter the host nucleus to cause infection, although how this is accomplished is unclear. To infect cells, the prototype PyV SV40 targets to the Nesprin-2 outer nuclear membrane protein and enters the ...
Luke Gohmann, Billy Tsai
doaj +2 more sources
Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Advanced Science, Volume 13, Issue 25, 4 May 2026.Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song +4 more
wiley +1 more source
Sun1 is preferentially incorporated into LINC complexes over Sun2.
, 2018 (A) Endogenous Nesprin1 and Nesprin2 immunoprecipitations of SUN proteins. GFP-SR-KASH outcompetes Nesprin1 binding but is recognized by Nesprin2 immunoprecipitation.
Christopher K. May (5309711) +1 more
core +1 more source
Quantum spin models for the SU(n)1 Wess–Zumino–Witten model
Nuclear Physics B, 2014 We propose 1D and 2D lattice wave functions constructed from the SU(n)1 Wess–Zumino–Witten (WZW) model and derive their parent Hamiltonians. When all spins in the lattice transform under SU(n) fundamental representations, we obtain a two-body Hamiltonian
Hong-Hao Tu +2 more
doaj +1 more source
Presence of meiotic telomere attachment in Sun1−/− mouse strains.
, 2014 (A) Telomere fluorescence in-situ hybridization (TeloFISH) in co-localization with Lamin B and SYCP3 immunofluorescence on representative 15 dpp (days past partum) Sun1+/+(Δex10-11) and littermate Sun1−/−(Δex10-11) testis sections (A, A′) and 17.5 dpf ...
Johannes Schmitt (244150) +7 more
core +1 more source
Emerin binding to p.G68D/p.G338S SUN1 is reduced in vivo.
, 2014 (A) SUN1 was immunoprecipitated from control (C) or MD-1 myoblast soluble lysates using 2383 SUN1 antibodies and samples Western blotted to detect co-immunopreciptated proteins.
Farhana Haque (484805) +10 more
core +1 more source
Characterisation of Enaptin and Sun1, two novel mammalian nuclear envelope proteins [PDF]
, 2004 The nucleus is a highly dynamic organelle showing migratory events during various developmental and cellular processes. These are made possible by its association with the microtubule network and, as shown recently, with the microfilament network.
Padmakumar, Velayuthan Chellammal
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Inner Nuclear Envelope Proteins SUN1 and SUN2 Play a Prominent Role in the DNA Damage Response [PDF]
, 2012 SummaryThe DNA damage response (DDR) and DNA repair are critical for maintaining genomic stability and evading many human diseases [1, 2]. Recent findings indicate that accumulation of SUN1, a nuclear envelope (NE) protein, is a significant pathogenic ...
Shao, Chunlin +6 more
core +1 more source
Autophagic Removal of Farnesylated Carboxy-Terminal Lamin Peptides
Cells, 2018 The mammalian nuclear lamina proteins—prelamin A- and B-type lamins—are post-translationally modified by farnesylation, endoproteolysis, and carboxymethylation at a carboxy-terminal CAAX (C, cysteine; a, aliphatic amino acid; X, any amino ...
Xiang Lu, Karima Djabali
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