Results 101 to 110 of about 149,980 (205)

Functional organization and dynamics of the cell nucleus

Frontiers in Plant Science, 2014
The highly ordered eukaryotic cell nucleus encapsulated by the nuclear envelope harbors the territorially organized chromatin and various nuclear bodies, and provides a relatively separate environment for replication, maintenance, transcription, and ...
Tongtong eGuo, Yuda eFang
doaj   +1 more source

Nuclear envelope interactions [PDF]

, 2014
The nuclear envelope is composed of the inner membrane and outer membrane, which is a continuation of the rough ER. Lipids of the nuclear envelope compossess signaling functions. Ganglioside GM1 helps to regulate the concentration of Ca2+ in the nucleus.
Štach, Martin
core  

Effects of GS-CA1 on nuclear envelope-associated early HIV-1 infection steps

Frontiers in Virology
The novel HIV-1 drugs GS-CA1 and the recently approved lenacapavir (GS-6207) target the viral structural protein capsid (CA). However, their multiple mechanisms of action have not been fully characterized.
Amita Singh, Victor Fourcassié, Victor Fourcassié, Karen Cristine Gonçalves Dos Santos, Hocine Chelbi, Natacha Merindol, Arnaud Droit, Arnaud Droit, Hugo Germain, Lionel Berthoux   +9 more
doaj   +1 more source

Nuclear Envelope: Torn Apart at Mitosis [PDF]

, 2002
The findings of two recent studies suggest a novel mechanism for nuclear envelope breakdown in which cytoplasmic dynein anchored on the outside of the nucleus generates tension, thus triggering tearing of the nuclear ...
Gönczy, P., Gönczy, Pierre
core   +1 more source

Protein kinase C activity modulates nuclear Lamin A/C dynamics in HeLa cells

Scientific Reports
The nuclear lamina serves important functions in the nucleus, providing structural support to the nuclear envelope and contributing to chromatin organization. The primary proteins that constitute the lamina are nuclear lamins whose functions are impacted
Chase C. Wesley, Dallin V. North, Daniel L. Levy   +2 more
doaj   +1 more source

The LINC complex ensures accurate centrosome positioning during prophase

Life Science Alliance
Centrosome positioning in prophase is essential for efficient spindle assembly. Here, we show that centrosome positioning requires LINC complex–mediated loading of dynein on the nuclear envelope.
Joana T Lima, António J Pereira, Jorge G Ferreira   +2 more
doaj   +1 more source

Emerin is necessary for microtubule-organizing center translocation to the nuclear envelope of muscle cells

Cell Death and Disease
During myogenic differentiation, the Microtubule-Organizing Center (MTOC) is relocated to the nuclear envelope by a molecular platform including Linker of Nucleoskeleton and Cytoskeleton (LINC) complex proteins, A Kinase Anchoring Proteins (AKAP9 and ...
Elisabetta Mattioli, Vittoria Cenni, Patrizia Sabatelli, Elisa Schena, Spartaco Santi, Chiara Fiorillo, Claudio Bruno, Antonella Pini, Melania Giannotta, Marco Cavallo, Costantino Errani, Eleonora Cattin, Daniela Benati, Alessandra Recchia, Giovanna Lattanzi   +14 more
doaj   +1 more source

The nuclear envelope and metastasis

Oncotarget, 2023
Hansen, Emily, Holaska, James M.
openaire   +2 more sources

An investigation into the role of lamin A in the progression of colorectal cancer [PDF]

, 2005
Nuclear lamins are type V intermediate filaments which form a proteinaceous meshwork, termed the nuclear lamina, which underlines the inner nuclear membrane and provides mechanical strength to the nucleus and maintains nuclear shape.
Willis, Naomi Daphne
core  

ERM proteins support perinuclear actin rim formation

Frontiers in Cell and Developmental Biology
The interaction of actin filaments with the nuclear envelope is essential for diverse cellular processes, including cell migration, nuclear positioning, and transcriptional control.
Yuval Hadad, Andrea Fracchia, Dagmawit Babele, Amit Ben Shushan, Gabi Gerlitz   +4 more
doaj   +1 more source