Results 131 to 140 of about 355,529 (299)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Tailoring tokamak error fields to control plasma instabilities and transport

Nature Communications
A tokamak relies on the axisymmetric magnetic fields to confine fusion plasmas and aims to deliver sustainable and clean energy. However, misalignments arise inevitably in the tokamak construction, leading to small asymmetries in the magnetic field known
SeongMoo Yang, Jong-Kyu Park, YoungMu Jeon, Nikolas C. Logan, Jaehyun Lee, Qiming Hu, JongHa Lee, SangKyeun Kim, Jaewook Kim, Hyungho Lee, Yong-Su Na, Taik Soo Hahm, Gyungjin Choi, Joseph A. Snipes, Gunyoung Park, Won-Ha Ko   +15 more
doaj   +1 more source

Erosion of thin boron films at the linear plasma device PSI-2 during deuterium discharges: Atomic and molecular spectroscopy of boron

Nuclear Materials and Energy
This study reports on deuterium plasma-boron layer interaction investigated at the linear plasma device PSI-2. In preparation, RF magnetron sputtering deposited 115nm thick boron layers onto tungsten substrates. Exposing the samples to a deuterium plasma
Marc Sackers, Oleksandr Marchuk, Anne Houben, Eduard Warkentin, Marcin Rasinski, Sebastijan Brezinsek, Arkadi Kreter   +6 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Innovative laser-based methods for monitoring fuel retention in ITER

Nuclear Materials and Energy
This paper addresses the challenge of tritium inventory management in ITER and future fusion reactors, highlighting the importance of accurate tritium measurement and its spatial distribution within the vacuum vessel. Given ITER’s operational constraints,
A. Huber, Ph. Andrew, G. Sergienko, J. Assmann, D. Castano, A. De Schepper, S. Friese, R. Greven, I. Ivashov, D. Kampf, Y. Krasikov, C.C. Klepper, H.T. Lambertz, Ph. Mertens, K. Mlynczak, G. Offermanns, B. Quinlan, K. Rasinska, M. Schrader, D. Van Staden, A. Terra, Xi Jiang, M. Zlobinski, V. Huber, A. Reutlinger, S. Brezinsek, Ch. Linsmeier   +26 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Report by the Joint-Core Team for the Establishment of Technology Bases Required for the Development of a Fusion DEMO Reactor [PDF]

, 2014
In accordance with the request of the Working Group on Fusion Research, the Nuclear Science and Technology Committee, the Subdivision on R&D Planning and Evaluation, the Council for Science and Technology, the Ministry of Education, Culture, Sports ...
OKANO, Kunihiko, TANAKA, Teruya, OZAKI, Akira, TANIGAWA, Hisashi, TOBITA, Kenji, YAMADA, Hiroshi, KASADA, Ryuta, TAKENAGA, Hidenobu, SAKAMOTO, Ryuichi, USHIGUSA, Kenkichi, KANEKO, Osamu, SAKAMOTO, Yoshiteru   +11 more
core  

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Electrothermal discharge by exploding of copper wires with different diameters

Scientific Reports
This paper explores the explosion behavior of copper wires with diameters between 0.16 mm and 0.50 mm, using an electrothermal discharge system comprising capacitors of total energy up to 1.11 kJ.
F. B. Diab, M. A. Abd Al-Halim, M. E. Abdel-kader   +2 more
doaj   +1 more source