Results 111 to 120 of about 384,818 (233)

Erosion of thin boron films at the linear plasma device PSI-2 during deuterium discharges: Atomic and molecular spectroscopy of boron

Nuclear Materials and Energy
This study reports on deuterium plasma-boron layer interaction investigated at the linear plasma device PSI-2. In preparation, RF magnetron sputtering deposited 115nm thick boron layers onto tungsten substrates. Exposing the samples to a deuterium plasma
Marc Sackers, Oleksandr Marchuk, Anne Houben, Eduard Warkentin, Marcin Rasinski, Sebastijan Brezinsek, Arkadi Kreter   +6 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Tailoring tokamak error fields to control plasma instabilities and transport

Nature Communications
A tokamak relies on the axisymmetric magnetic fields to confine fusion plasmas and aims to deliver sustainable and clean energy. However, misalignments arise inevitably in the tokamak construction, leading to small asymmetries in the magnetic field known
SeongMoo Yang, Jong-Kyu Park, YoungMu Jeon, Nikolas C. Logan, Jaehyun Lee, Qiming Hu, JongHa Lee, SangKyeun Kim, Jaewook Kim, Hyungho Lee, Yong-Su Na, Taik Soo Hahm, Gyungjin Choi, Joseph A. Snipes, Gunyoung Park, Won-Ha Ko   +15 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Innovative laser-based methods for monitoring fuel retention in ITER

Nuclear Materials and Energy
This paper addresses the challenge of tritium inventory management in ITER and future fusion reactors, highlighting the importance of accurate tritium measurement and its spatial distribution within the vacuum vessel. Given ITER’s operational constraints,
A. Huber, Ph. Andrew, G. Sergienko, J. Assmann, D. Castano, A. De Schepper, S. Friese, R. Greven, I. Ivashov, D. Kampf, Y. Krasikov, C.C. Klepper, H.T. Lambertz, Ph. Mertens, K. Mlynczak, G. Offermanns, B. Quinlan, K. Rasinska, M. Schrader, D. Van Staden, A. Terra, Xi Jiang, M. Zlobinski, V. Huber, A. Reutlinger, S. Brezinsek, Ch. Linsmeier   +26 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Electrothermal discharge by exploding of copper wires with different diameters

Scientific Reports
This paper explores the explosion behavior of copper wires with diameters between 0.16 mm and 0.50 mm, using an electrothermal discharge system comprising capacitors of total energy up to 1.11 kJ.
F. B. Diab, M. A. Abd Al-Halim, M. E. Abdel-kader   +2 more
doaj   +1 more source