Results 31 to 40 of about 320,326 (253)

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

Numerical Analysis of the Electric Potential and Field in Concentric Spherical Grids of an IR-IECF Device and Investigation of Particle Dynamics Using Particle Tracing [PDF]

open access: yesفیزیک کاربردی ایران
In inertial electrostatic confinement (IEC) devices, an electrostatic potential well accelerates ions toward the center of a vacuum chamber, and the grid geometry plays a decisive role in field uniformity and particle trajectories.
Maryam Ghapanvari, Ali Bagheri
doaj   +1 more source

Reassessing Bone Marrow Aspirate and Trephine Biopsies in Staging for Paediatric and Young Adult Patients With Ewing Sarcoma and Rhabdomyosarcoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma (ES) and rhabdomyosarcoma (RMS) are aggressive malignancies in children and adolescents where metastases impact prognosis. 18F‐fluoro‐2‐deoxy‐d‐glucose positron emission tomography/computed tomography (FDG‐PET/CT) and bone marrow aspirate and trephine biopsies (BMAT) are used to identify disease involvement.
Imogen Andrews   +3 more
wiley   +1 more source

Parametric profiles of plasma current sheath in argon plasma focus during axial phase

open access: yesDiscover Applied Sciences
This study presents the findings of theoretical and experimental studies into the dynamical behaviors of the plasma current sheath (PCS) and its parameters during the axial phase of plasma focus at the inter-electrode discharge of a 2.2 kJ (EAEA-PF1 ...
Kamal M. Ahmed   +4 more
doaj   +1 more source

Compact permanent magnet-based electron cyclotron resonance plasma source for surface nitriding of steel

open access: yesResults in Physics
This study investigates the efficiency of a compact Electron Cyclotron Resonance (ECR) plasma source, utilizing a permanent magnet array, for the low-temperature nitriding of AISI 304 stainless steel.
Soolmaz Jamali   +2 more
doaj   +1 more source

Design of a Prototypical Mock-Up for the Experimental Investigation of WCLL First-Wall Performances

open access: yesEnergies, 2023
A large research effort is currently ongoing within the framework of the EUROfusion consortium for the study and design of a water-cooled lithium–lead (WCLL) breeding blanket (BB).
Pietro Maccari   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Photoacoustic Laser System for Food Fraud Detection

open access: yesSensors, 2021
Economically motivated adulterations of food, in general, and spices, in particular, are an emerging threat to world health. Reliable techniques for the rapid screening of counterfeited ingredients in the supply chain need further development.
Luca Fiorani   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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