Results 111 to 120 of about 1,802,430 (358)
Gene Expression Analysis from Nuclear Poly(A)+ RNA
BioTechniques, 2002 Quantitation of the level of specific mRNA involves the isolation of total RNA or poly(A)+ RNA as a starting material. Thus, this result is the sum of the transcription and degradation of mRNA.
K. Matsuda +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Nuclear Organisation of Immunoglobulin Genes
Directions in Science, 2002 The function of a B cell is to produce antibodies which can respond to the numerous foreign antigens which we encounter. Since there are only a limited number of immunoglobulin genes (Ig) this is achieved through a process whereby variable (V), diversity (D) and joining (J) gene segments of immunoglobulin genes are rearranged in different orders to ...
M. Merkenschlager +10 more
openaire +2 more sources
Intracompartmental and Intercompartmental Transcriptional Networks Coordinate the Expression of Genes for Organellar Functions [PDF]
, 2011 Genes for mitochondrial and chloroplast proteins are distributed between the nuclear and organellar genomes. Organelle biogenesis and metabolism, therefore, require appropriate coordination of gene expression in the different compartments to ensure ...
Haberer, Georg +4 more
core +2 more sources
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
pteridium nuclear gene phylogeny
, 2019 Raw amplicon sequence data and raw reads of from GBS library. Also all code and analyses required to process raw data.
Wolf, Paul G +7 more
openaire +4 more sources
Role of lamins in 3D genome organization and global gene expression
Nucleus, 2019 Genome-wide mapping of lamin-B1-genome interactions has shown that gene-poor and transcriptionally inactive genomic regions are associated with the nuclear lamina.
Youngjo Kim, Xiaobin Zheng, Yixian Zheng
doaj +1 more source
Sex-Biased Gene Flow Among Elk in the Greater Yellowstone Ecosystem [PDF]
, 2014 We quantified patterns of population genetic structure to help understand gene flow among elk populations across the Greater Yellowstone Ecosystem.
Anderson, Neil +16 more
core +1 more source
An agent-based model for mRNA export through the nuclear pore complex. [PDF]
, 2014 mRNA export from the nucleus is an essential step in the expression of every protein- coding gene in eukaryotes, but many aspects of this process remain poorly understood.
Azimi, Mohammad +3 more
core +2 more sources
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source