Results 121 to 130 of about 595,659 (257)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Can Nuclear Imaging Detect Trained Immunity in Cardiovascular Disease? [PDF]

Arterioscler Thromb Vasc Biol
Teunissen AJP, van Leent MMT.
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Experience of [177Lu]Lu-PSMA-617-administration using totally implantable venous access port: simulated experiments and clinical SPECT analyses

EJNMMI Research
Adèle Lombard, Samuel Journo, Timothée Zaragori, Pierre Olivier, Marine Claudin, Pierre-Yves Marie, Marie Bros, Manon Bordonné, Antoine Verger, Nicolas Veran, Quentin Citerne, Laetitia Imbert, Caroline Boursier   +12 more
doaj   +1 more source

Beyond Conventional Imaging: Nuclear Imaging in Rheumatoid Arthritis. [PDF]

J Clin Med
Sugden H, Di Matteo A, Mankia K.
europepmc   +1 more source

Phenotyping heart failure by nuclear imaging of myocardial perfusion, metabolism, and molecular targets. [PDF]

Eur Heart J Cardiovasc Imaging, 2023
Saraste A, Knuuti J, Bengel F.
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Ablation-induced collagen exposure enables dual-modal nuclear imaging-guided local radionuclide therapy. [PDF]

J Nanobiotechnology
Wang P, Li N, Chen Q, Yao Y, Ren Y, Liu S, Hou X, Zhang B, Xiong F, Zhu X, Yang Z, Ni D, Yu B.   +12 more
europepmc   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

The role of nuclear imaging in detection of coronary artery disease: a comprehensive review. [PDF]

Am J Transl Res
Zhou P, Wang F.
europepmc   +1 more source