Results 141 to 150 of about 595,659 (257)

Multimodal Nuclear Imaging Response as a Prognostic Indicator Following Spine Stereotactic Body Radiation Therapy. [PDF]

Adv Radiat Oncol
Dibs K, Tocaj G, Palmer J, Raval R, Beyer S, Zhu S, Singh R, Gogineni E, Kumar P, Lonser R, Thomas E, Grecula J, Chakravarti A, Xu D, Elder J, Bourekas E, Blakaj DM.   +16 more
europepmc   +1 more source

Clinical utility of nuclear imaging in the evaluation of pediatric adrenal neoplasms. [PDF]

Front Oncol, 2022
Fargette C, Shulkin B, Jha A, Pacak K, Taïeb D.   +4 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

A Trifunctional, Rare-Earth Theranostic Chelator Platform to Enable Diagnostic Nuclear Imaging, Surgical Resection, and Radiotherapy. [PDF]

J Am Chem Soc
Joaqui-Joaqui MA, Sands GG, Śmiłowicz D, Gork MJ, Aluicio-Sarduy E, Barnhart TE, Engle JW, Boros E.   +7 more
europepmc   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Development of lisinopril radioconjugates for nuclear imaging of the angiotensin converting enzyme. [PDF]

Eur J Nucl Med Mol Imaging
Vaccarin C, Beyer D, Moiseeva A, Favaretto C, van der Meulen NP, Hunkeler BD, Rupp NJ, Marzaro G, Schibli R, Müller C.   +9 more
europepmc   +1 more source

Potential of Nuclear Imaging Techniques to Study the Oral Delivery of Peptides. [PDF]

Pharmaceutics, 2022
Saxena T, Sie C, Lin K, Ye D, Saatchi K, Häfeli UO.   +5 more
europepmc   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

The Utility of Nuclear Imaging in Hypertrophic Cardiomyopathy: A Narrative Review. [PDF]

J Clin Med
Pradeep Kundur S, Malik A, Sivalokanathan S.   +2 more
europepmc   +1 more source

Nuclear Imaging in Pediatric Cardiology: Principles and Applications. [PDF]

Front Pediatr, 2022
Venet M, Friedberg MK, Mertens L, Baranger J, Jalal Z, Tlili G, Villemain O.   +6 more
europepmc   +1 more source