Results 121 to 130 of about 13,614,081 (295)

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Preliminary Studies of Thermal Wavelength Approximation in 208Pb and 91Zr hot Nuclei [PDF]

ITB Journal of Engineering Science, 2006
Level density parameters of 208Pb and 91Zr in equilibrium states have been calculated with a new fugacity approximation namely a thermal wavelength approximation. In this approximation, the fugacity is directly proportional to the nucleon density.
R. Kurniadi
doaj  

A new nuclear level density formula including shell and pairing correction in the light of a microscopic model calculation

, 1996
In the framework of the statistical model, the analytical approximation to the spin-dependent level density is improved by introducing in a new way the shell and pairing effects.
S. Goriely, Goriely, Stéphane
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Probing the limits of statistical neutron capture for the r process: Experimental constraints on 141Cs nuclear level densities

Physics Letters B
The r-process abundance peaks, particularly near mass number A ∼ 130, reflect underlying nuclear structure effects such as closed neutron shells, yet modeling the nucleosynthesis in this region remains hindered by uncertain neutron-capture rates.
B. Greaves, D. Mücher, A. Spyrou, S. Goriely, D. Rochman, H.C. Berg, D.L. Bleuel, J.A. Clark, C. Dembski, P.A. Deyoung, E. Good, C.M. Harris, A.J. Koning, A.C. Larsen, S.N. Liddick, S.M. Lyons, M. Markova, M.J. Mogannam, G. Owens-Fryar, A. Palmisano-Kyle, A.L. Richard, E.K. Ronning, D. Santiago-Gonzalez, G. Savard, M.K. Smith, A. Sweet, A. Tsantiri   +26 more
doaj   +1 more source

Calculation of nuclear level density parameters of some light deformed medical radionuclides using collective excitation modes of observed nuclear spectra

, 2009
In this study the nuclear energy level density based on nuclear collective excitation mechanism has been identified in terms of the low-lying collective level bands near the neutron binding energy.
Akti, N. N., Tel, E., Sarac, HİLAL, Okuducu, S., Bolukdemir, MUSTAFA HİCABİ   +4 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

NUCLEAR LEVEL DENSITIES

Annual Review of Nuclear Science, 1972
J R Huizenga, L G Moretto
openaire   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source