Results 101 to 110 of about 13,614,081 (295)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Use of Single Particle Level from Experimental Data to Find Level Density Pre-Equilibrium Region of Nuclear Reactions Reaction

مجلة بغداد للعلوم
In this study the new formula of the single particle levels was obtained using the experimental data of the level density parameter and this new formula was substituted into the four formulae of partial level density corrected for pairing these formulae ...
Tibba Hassan Madhi, Ali Dawoud Salloum
doaj   +1 more source

Dynamical phase transitions in quantum mechanics

EPJ Web of Conferences, 2012
The nucleus is described as an open many-body quantum system with a non-Hermitian Hamilton operator the eigenvalues of which are complex, in general. The eigenvalues may cross in the complex plane (exceptional points), the phases of the eigenfunctions ...
Rotter Ingrid
doaj   +1 more source

Relation between nuclear level density parameters and mass shell corrections

, 1969
Previous work by Gilbert and Cameron has demonstrated a linear relation between the nuclear level density parameter a and the mass shell correction S. However, different relations were obtained for deformed and undeformed nuclei.
P. J. Brancazio, A. G. W. Cameron
core   +1 more source

Microscopic model for the collective enhancement of nuclear level densities

, 2020
A microscopic method for calculating nuclear level density (NLD) is developed, based on the framework of energy density functionals. Intrinsic level densities are computed from single-quasiparticle spectra obtained in a finite-temperature self-consistent
Vretenar, Dario, Nikšić, Tamara, Zhao, Jie, Tamara Nikšić, Jie Zhao, Dario Vretenar   +5 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Imprint of pairing correlation in (n, γ) and Maxwellian-averaged cross sections of an odd-odd 166Ho nucleus

Physics Letters B
The present paper investigates the impact of pairing correlation on the nuclear level density (NLD) and radiative strength function (RSF) of an odd-odd and rare-earth 166Ho nucleus. By employing the exact thermal pairing (EP) solution in conjunction with
Le Tan Phuc, Tran Vu Dong, Nguyen Dinh Dang, Bui Minh Hue, Le Thi Quynh Huong, Balaram Dey, Nguyen Ngoc Anh, Nguyen Quang Hung   +7 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Development of a new Nuclear Level Density Database

A new nuclear level density (NLD) database has been developed to address uncertainties in NLDs by hosting data from diverse experimental techniques, enabling users to search, visualize, compare, and fit NLD data with best-fit parameters and quantified ...
Rathi, Chirag
core   +2 more sources

Nuclear weapons: the state of play [PDF]

, 2013
The Crawford School of Public Policy’s Centre for Nuclear Non-Proliferation and Disarmament (CNND) this week launched in Geneva a major book-length report authoritatively documenting the unhappily diminishing global enthusiasm for nuclear disarmament ...
Ramesh Thakur, Gareth Evans
core