Results 81 to 90 of about 3,438,672 (302)

Structural basis of the oligomerization of anti-silencer Ler from enterohemorrhagic E. coli (EHEC) [PDF]

Structural Dynamics
The locus of enterocyte effacement-encoded regulator (Ler) is a master transcriptional activator essential for the virulence of enterohemorrhagic and enteropathogenic Escherichia coli.
Guanghao Wang, Bo Duan, Bin Xia
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Brain functional reorganization in pediatric patients with spinal cord injury and the impact of motor imagery training on it: a preliminary study

IBRO Neuroscience Reports
To study the brain functional alterations of children after spinal cord injury (SCI) and explore their changes after motor imagery training (MIT), revealing brain functional reorganizations in pediatric SCI and finding possible neural mechanisms of MIT ...
Ling Wang, Beining Yang, Qunya Qi, Haotian Xin, Yu Wang, Yulong Jia, Qian Chen, Weimin Zheng, Xin Chen, Tengfei Liang, Chuchu Sun, Jubao Du, Baowei Li, Jie Lu, Nan Chen   +14 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Efficient Experimental Design for Measuring Magnetic Susceptibility of Arbitrarily Shaped Materials by MRI [PDF]

, 2018
This work was funded by the Institute for Basic Science, under grant IBS-R015-D1. The SQUID measurement was provided by Dr. Seung-young Park from Korea Basic Science Institute (KBSI).
Seon-ha Hwang, Seung-Kyun Lee
core   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Research Results Obtained by the Use of High-Throughput Nuclear Magnetic Resonance System [PDF]

, 2013
The nuclear magnetic resonance (NMR) system was an indispensable measurement equipment and used in a variety of chemical research areas. The ladder-ratio of synthesized polyamide was estimated by the integral values of ^1H NMR spectra.
倉持, 甚也, TOTANI, Kiichiro, TSUBOMURA, Taro, 戸谷, 希一郎, 坪村, 太郎, KURAMOCHI, Jinya, 横山, 明弘, YOKOYAMA, Akihiro, 高石, 和人, TAKAISHI, Kazuto   +9 more
core   +1 more source

Analysis of the electronic structure of the primary electron donor of photosystem I of Spirodela oligorrhiza by photochemically induced dynamic nuclear polarization (photo-CIDNP) solid-state nuclear magnetic resonance (NMR) [PDF]

, 2020
This research has been supported by the Dutch Science Organization (NWO (grant no. 818.02.019)), the Deutsche Forschungsgemeinschaft (grant nos. MA 497/2-1 and MA 497/11-1), the Alexander von Humboldt-Stiftung, and the People Programme (Marie Curie ...
Alia, A., Alia, Alia, Bode, B.E., Groot, H.J.M. de, Kurle, Patrick, Matysik, J., Neugebauer, Johannes, Eschenbach, Patrick, Matysik, Jörg, Bode, Bela Ernest, Janssen, G.J., Kurle, P., Neugebauer, J., Janssen, Geertje, de Groot, Huub, Eschenbach, P.   +15 more
core   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Integrating a prospective pilot trial and patient-derived xenografts to trace metabolic changes associated with acute myeloid leukemia

Journal of Hematology & Oncology, 2016
Despite the considerable progress in understanding the molecular bases of acute myeloid leukemia (AML), new tools to link disease biology to the unpredictable patient clinical course are still needed.
Matteo G. Carrabba, Laurette Tavel, Giacomo Oliveira, Alessandra Forcina, Giacomo Quilici, Francesca Nardelli, Cristina Tresoldi, Alessandro Ambrosi, Fabio Ciceri, Massimo Bernardi, Luca Vago, Giovanna Musco   +11 more
doaj   +1 more source