Results 61 to 70 of about 3,438,672 (302)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Comparative cost-effectiveness analyses of cardiovascular magnetic resonance and coronary angiography combined with fractional flow reserve for the diagnosis of coronary artery disease. [PDF]

, 2014
According to recent guidelines, patients with coronary artery disease (CAD) should undergo revascularization if significant myocardial ischemia is present.
Pilz, G., Steffen E Petersen, Pilz, G, Petersen, SE, Wasserfallen, J-B, Guenter Pilz, Petersen, S.E., Favre, David, Petersen, Steffen E., Anja Wagner, Schwitter, J.J., Pinget, C, Favre, D., Wagner, A, Wagner, A., Jean-Blaise Wasserfallen, Karine Moschetti, Moschetti, K., Moschetti, Karine, Wasserfallen, JB, Schwitter, J, Schwitter, Juerg, Wasserfallen, Jean-Blaise, David Favre, Schwitter, JJ, Christophe Pinget, Pinget, Christophe, Wasserfallen, J.B., Pilz, Guenter, Pinget, C., Wagner, Anja, Juerg J Schwitter, Moschetti, K, Favre, D   +33 more
core   +1 more source

Application of a portable nuclear magnetic resonance surface probe to porous media

, 2022
S.19-27A portable nuclear magnetic resonance (NMR) surface probe was used to determine the time-dependent self-diffusion coefficient D(t) of water molecules in two fluid-filled porous media.
Arnold, W., Marko, A., Wolter, B.
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Pediatric Mediastinal Gray Zone Lymphoma With Germline TET2 Heterozygous Variant

Pediatric Blood &Cancer, EarlyView.
Matthew R. Schuelke, Julia Wang, Haley Newman, Evelyn Kurpiewski, Anne Reilly, Susan R. Rheingold, Gerald Wertheim, Moe Takeda, Daniel J. Zheng, Kaitlin Devine   +9 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Rapid magnetic resonance tissue relaxometry in the steady state [PDF]

, 2015
Longitudinal (T1) and transverse (T2) relaxation are the most fundamental physical processes governing the signal intensity and the soft tissue contrast in magnetic resonance imaging (MRI).
Heule, Rahel Maria, Heule, R. ; https://orcid.org/   +1 more
core   +1 more source

Paired-pulse TMS of premotor cortex produces non-linear suppressive effects on neural activity in the targeted network - a TMS-fMRI study

NeuroImage
Background: Transcranial magnetic stimulation (TMS) activates neural circuits in targeted and connected areas, yet it remains unclear how “TMS-dose” relates to local or network responses, particularly outside the primary motor hand area.
Laerke Gebser Krohne, Sofus Nygaard, Maud Eline Ottenheijm, Marie Louise Liu, Axel Thielscher, Hartwig Roman Siebner, Kristoffer Hougaard Madsen   +6 more
doaj   +1 more source