Results 111 to 120 of about 1,023,868 (347)
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Dense Stellar Matter with Strange Quark Matter Driven by Kaon Condensation
, 2011 The core of neutron-star matter is supposed to be at a much higher density than the normal nuclear matter density for which various possibilities have been suggested such as, for example, meson or hyperon condensation and/or deconfined quark or color ...
Kim, Kyungmin +2 more
core +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Particles, 2019 We give a pedagogical review of the properties of the various meson condensation phases triggered by a large isospin or strangeness imbalance. We argue that these phases are extremely interesting and powerful playground for exploring the properties of ...
Massimo Mannarelli
doaj +1 more source
Heavy-Ion Collisions toward High-Density Nuclear Matter. [PDF]
Entropy (Basel), 2022 Nagamiya S.
europepmc +1 more source
Nuclear positioning: A matter of life [PDF]
Seminars in Cell & Developmental Biology, 2018 Cell organization, and in particular how organelles are distributed in the cell, is often used by physio-pathologists to visually identify cell types in an organism. Behind this simple fact, it suggests that the positioning of sub-cellular structures is not occurring randomly but by active manners.
openaire +4 more sources
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Chemical Functionalization Effects on Cubane-Based Chain Electronic Transport
Advances in Condensed Matter Physics, 2015 We report electronic structure calculations in chemically functionalized linear cubane-based chains. The effects of covalent chemical attachments on chain transport properties are examined with nonorthogonal tight-binding model (NTBM) considering ...
Konstantin P. Katin, Mikhail M. Maslov
doaj +1 more source