Results 111 to 120 of about 1,052,179 (350)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Scientific ReportsWe propose the use of the vibrational quantum defect (VQD) to select the best energy function that could better model the vibrational energy levels of diatomic molecules.We report an analysis of accurate experimental RKR energy data obtained from ...
Haikel Jelassi +2 more
doaj +1 more source
Hybrid stars that masquerade as neutron stars
, 2004 We show that a hybrid (nuclear + quark matter) star can have a mass-radius relationship very similar to that predicted for a star made of purely nucleonic matter. We show this for a generic parameterization of the quark matter equation of state, and also
Baldo M. +5 more
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Multifragmentation, Clustering, and Coalescence in Nuclear Collisions [PDF]
, 2005 Nuclear collisions at intermediate, relativistic, and ultra-relativistic energies offer unique opportunities to study in detail manifold fragmentation and clustering phenomena in dense nuclear matter. At intermediate energies, the well known processes of
Scherer, Stefan, Stocker, Horst
core +2 more sources
, 2008 In this paper, we calculate properties of the spin polarized asymmetrical nuclear matter and neutron star matter, using the lowest order constrained variational (LOCV) method with the $AV_{18}$, $Reid93$, $UV_{14}$ and $AV_{14}$ potentials.
A. Vidaurre +4 more
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Chiral Symmetry Restoration and Pion Interaction in Nuclear Matter [PDF]
, 1998 G. Chanfray, D. Davesne
openalex +1 more source