Results 141 to 150 of about 1,230,906 (339)

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls   +9 more
wiley   +1 more source

Spinodal in asymmetric nuclear matter [PDF]

open access: yesarXiv, 2003
The phase diagram of nuclear matter is quite rich - it shows such phenomena as phase-transitions, formation of condensates, clustering, etc. From the analysis of the spinodal instability, one can learn about the region of liquid-gas coexistence in nuclear matter at low densities and finite isospin asymmetries.
arxiv  

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti   +8 more
wiley   +1 more source

Hadrons in Nuclear Matter

open access: yesEPJ Web of Conferences, 2017
We review the achievements of the project B.5, that deals with the calculation of in-medium properties of vector mesons and an analysis of their experimental signals, with a particular emphasis on the ω photoproduction data from CBELSA/TAPS. Other topics addressed include color transparency, pion electroproduction on nucleons, the Primakoff effect for ...
openaire   +3 more sources

Relativistic Chiral Theory of Nuclear Matter and QCD Constraints [PDF]

open access: yesarXiv, 2009
We present a relativistic chiral theory of nuclear matter which includes the effect of confinement. Nuclear binding is obtained with a chiral invariant scalar background field associated with the radial fluctuations of the chiral condensate Nuclear matter stability is ensured once the scalar response of the nucleon depending on the quark confinement ...
arxiv  

Meson Condensation

open access: yesParticles, 2019
We give a pedagogical review of the properties of the various meson condensation phases triggered by a large isospin or strangeness imbalance. We argue that these phases are extremely interesting and powerful playground for exploring the properties of ...
Massimo Mannarelli
doaj   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Higher-dimensional non-extremal Reissner-Nordstrom black holes, scalar perturbation and superradiance: An analytical study

open access: yesPhysics Letters B, 2021
The superradiant stability of asymptotically flat higher dimensional non-extremal Reissner-Nordstrom black holes under charged massive scalar perturbation is analytically studied.
Jia-Hui Huang   +2 more
doaj  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Hadronization in Cold Nuclear Matter [PDF]

open access: yesNuclear Physics A, 2007
I review a recently proposed scaling analysis of hadron suppression in Deeply Inelastic Scattering on nuclear targets measured at the HERMES experiment. The analysis can distinguish 2 competing explanations for the observed suppression, namely, quark radiative energy loss with long hadron formation times, and prehadron nuclear absorption with ...
openaire   +2 more sources

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