Results 101 to 110 of about 1,100,780 (314)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

THERANOSTICS: NUCLEAR MEDICINE IN PROSTATE CANCER

open access: yesHematology, Transfusion and Cell Therapy
Summary: Theranostic Nuclear Medicine is based on the idea of combining the same molecule (or drug) with different radioisotopes, both for diagnosis and treatment, a concept that emerged in the early 1940s with thyroid diseases.
Marina Camargo ETCHEBEHERE   +3 more
doaj   +3 more sources

Nuclear medicine in tropical diseases

open access: yesBrazilian Archives of Biology and Technology, 2002
Tropical diseases affect more people in the world than any other kind of disease, but scintigraphic data on that matter are not so frequent in the literature.
Braga Francisco José Hossri Nogueira
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Rare earth elements in nuclear medicine [PDF]

open access: yesСаратовский научно-медицинский журнал, 2014
The review focuses on the key applications of stable and radioactive isotopes of rare earth elements in the technology of nuclear medicine, radionuclide diagnostics and therapy, as well as magnetic resonance imaging and binary radiotherapy technologies.
Kodina G.E., Kulakov V.N., Sheino I.N.
doaj  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Cardiac & Lung Nuclear Medicine Exams

open access: yesIranian South Medical Journal, 2011
This book has three chapters: Heart, lung and radiation protection. In each chapter, indications of scans, radiopharaceuticals the study performance, patient preparation, report and also possible problems were discussed.
Majid Assadi, Masood Moslehi
doaj  

What are the expectations of patients regarding the communication of nuclear imaging results? Insights from a French national survey of 723 patients

open access: yesBMJ Open
Objectives There are still some controversies regarding the role of nuclear medicine practitioners in delivering imaging findings to the patients as well as content and magnitude of information to be delivered.
David Taïeb   +7 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Perspectives of nuclear medicine professionals on artificial intelligence and educational implications

open access: yesDiscover Artificial Intelligence
Objective We aimed to evaluate nuclear medicine professionals’ attitudes and perceptions of artificial intelligence (AI) in their field and medicine in general.
Hongyan Yin, Dai Shi, Can Meng
doaj   +1 more source

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