Results 91 to 100 of about 6,917,354 (302)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Swiss survey on hybrid imaging CTs doses in Nuclear Medicine and proposed national dose reference levels [PDF]

, 2018
A multidisciplinary working group led by the Swiss Federal Office of Public Health was formed to plan and perform a nationwide survey of patient radiation exposure from computed tomography (CT) in hybrid devices across Nuclear Medicine departments.
Reto Linder, Nicolas Stritt, Stritt, N., Stritt, Nicolas, Strobel, K., Lima, Thiago V.M., Thiago V.M. Lima, Klaus Strobel, Gnesin, Silvano, Gnesin, S., Linder, Reto, Lima, TVM, Linder, R., Nick Ryckx, Ryckx, Nick, Silvano Gnesin, Ryckx, N., Strobel, Klaus, Ryckx N, Strobel K, Gnesin S, Lima TVM, Stritt N, Linder R   +23 more
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Development and Validation of a Clinical Radiomics Nomogram for Predicting Early Recurrence After Microwave Ablation in Hepatocellular Carcinoma Patients With Type 2 Diabetes

Cancer Management and Research
Ze Sun,1,* Neng Wang,2,* Xufan Wu,1,* Tianyi Wang,1 Dong Liu,1 Yiran Zou,2 Ruilin He,1 Ningyang Jia11Department of Imaging Medicine and Nuclear Medicine, Eastern Hepatobiliary Surgery Hospital, Shanghai, People’s Republic of China;
Sun Z, Wang N, Wu X, Wang T, Liu D, Zou Y, He R, Jia N   +7 more
doaj  

Continuous bed motion versus step-and-shoot acquisition in LAFOV PET/CT: insights from multi-phantom and patient studies

EJNMMI Physics
Background Continuous bed motion (CBM) allows flexible extension of the scan range compared to conventional step‑and‑shoot (S&S) acquisition but has not yet been evaluated in long axial field‑of‑view (LAFOV) PET/CT. This study systematically assessed the
P. M. Linder, W. Lan, E. Calderón, I. Rausch, C. la Fougère, F. P. Schmidt   +5 more
doaj   +1 more source

International consensus on clinical use of presynaptic dopaminergic positron emission tomography imaging in parkinsonism.

Presynaptic dopaminergic positron emission tomography (PET) imaging serves as an essential tool in diagnosing and differentiating patients with suspected parkinsonism, including idiopathic Parkinson's disease (PD) and other neurodegenerative and non ...
Prior, J.O., Dou, X., Cahid Civelek, A., Zhou, R., Li, X., Wang, J., Carrio, I., Kang, K.W., Murakami, K., Tian, M., Watanabe, Y., Zhong, Y., Jin, C., Lu, J., Zuo, C., Zhang, H., Yu, C., Liu, F.   +17 more
core   +1 more source

[Nuclear medicine in Europe: education]. [PDF]

, 2012
Item does not contain fulltextThe technical developments that have taken place in the preceding years (PET, hybrid imaging) have changed nuclear medicine.
Gruning, T., Mottaghy, Felix, Freudenberg, L.S., Hellwig, D., Garai, I., Freudenberg, L. S., Gruening, T., Mottaghy, F.M., Franzius, C., Gotthardt, M., Krause, T., Leitha, T., Krause, Thomas Michael, Biermann, M., Mottaghy, F. M.   +14 more
core   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Nuclear medicine imaging of neuroendocrine tumours [PDF]

Clinical Medicine, 2012
#### Key points Neuroendocrine tumours (NETs) are slow growing but potentially malignant, increasing in incidence due to advances in hormone and tumour markers assays improving detection Conventional imaging is routinely used for localisation but sensitivity is suboptimal due both to small ...
openaire   +2 more sources

Summary: EANM/SNMMI Release Joint Guideline/Procedure Standard for [F]FDG Hybrid PET Use in Infection and Inflammation in Adults, Version 2.0.

A joint task force of subject-matter experts from the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI) recently released a revised and updated guideline/procedure standard for indications ...
Jamar, F., Israel, O., Pelletier-Galarneau, Matthieu, Gheysens, O., Abikhzer, G., Israel, Ora, Pelletier-Galarneau, M., Gheysens, Olivier, Jamar, François, Treglia, Giorgio, Treglia, G., Abikhzer, Gad   +11 more
core   +1 more source