The use of system dynamics group model building for analysing event causality within the nuclear industry [PDF]
, 2010 Currently the most frequently used tools for investigating and learning from industrial accidents are based on linear, reductionist models of event causality.
Carhart, NJ, Yearworth, M
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Complex models of nodal nuclear data [PDF]
, 2011 During the core simulations, nuclear data are required at various nodal thermal-hydraulic andfuel burnup conditions. The nodal data are also partially affected by thermal-hydraulic andfuel burnup conditions in surrounding nodes as these change the ...
Dufek, Jan,
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Theoretical study of cross sections of proton-induced reactions on cobalt
Nuclear Engineering and Technology, 2018 Nuclear fusion may be among the strongest sustainable ways to replace fossil fuels because it does not contribute to acid rain or global warming. In this context, activated cobalt materials in corrosion products for fusion energy are significant in ...
Mustafa Yiğit
doaj +1 more source
Opencg: A Combinatorial Geometry Modeling Tool for Data Processing and Code Verification [PDF]
, 2015 Combinatorial Geometry (CG) is one formulation for computational geometric models that is commonly used in many neutron transport simulation codes. The use of CG is advantageous since it permits an accurate yet concise representation of complex reactor ...
Forget, Benoit Robert Yves +2 more
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Interspecies somatic cell nuclear transfer is dependent on compatible mitochondrial DNA and reprogramming factors [PDF]
, 2011 Interspecies somatic cell nuclear transfer (iSCNT) involves the transfer of a nucleus or cell from one species into the cytoplasm of an enucleated oocyte from another.
St. John Justin C. +22 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
The Best-Estimate Plus Uncertainty (BEPU) Challenge in the Licensing of Nuclear Power Plants (NPP) [PDF]
, 2011 Within the licensing process of the Atucha II PHWR (Pressurized Heavy Water Reactor) the BEPU (Best Estimate Plus Uncertainty) approach has been selected for issuing of the Chapter 15 on FSAR (Final Safety Analysis Report).
Oscar Mazzantini, Francesco D’Auria
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Applying Human-performance Models to Designing and Evaluating Nuclear Power Plants: Review Guidance and Technical Basis [PDF]
, 2009 Human performance models (HPMs) are simulations of human behavior with which we can predict human performance. Designers use them to support their human factors engineering (HFE) programs for a wide range of complex systems, including commercial nuclear ...
J.M. O'Hara, O'Hara, J. M.
core +1 more source