Results 81 to 90 of about 1,978,560 (292)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Nonextensive critical effects in relativistic nuclear mean field models*
EPJ Web of Conferences, 2011 We present a possible extension of the usual relativistic nuclear mean field models widely used to describe nuclear matter towards accounting for the influence of possible intrinsic fluctuations caused by the environment.
Rożynek J., Wilk G.
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Atmosphere, 2020 Grounded in a social scientific research approach, the present case study traces the shift in the German nuclear regulatory culture from prevention to preparedness, the latter of which builds upon decision support systems for nuclear emergency management.
Tudor B. Ionescu
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Does nuclear matter bind at large $N_c$?
, 2011 The existence of nuclear matter at large $N_{c}$ is investigated in the framework of effective hadronic models of the Walecka type. This issue is strongly related to the nucleon-nucleon attraction in the scalar channel, and thus to the nature of the ...
Bonanno, Luca, Giacosa, Francesco
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Select the Optimized Effective Dose to Reduce Nuclear Radiations in Pediatric Nuclear Medicine
World Journal of Nuclear Medicine, 2014 Many techniques and research models on calculating and reducing the nuclear radiation dose on pediatric nuclear medicine procedure have been developed and reported in recent years.
Ying Bai, Dali Wang
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Bertini intra-nuclear cascade implementation in Geant4
, 2003 We present here a intra-nuclear cascade model implemented in Geant4 5.0. The cascade model is based on re-engineering of INUCL code. Models included are Bertini intra-nuclear cascade model with exitons, pre-equilibrium model, nucleus explosion model ...
Heikkinen, Aatos +2 more
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Assessment of internal refractive index profile of stochastically inhomogeneous nuclear models via analysis of two-dimensional optical scattering patterns. [PDF]
J Biomed Opt, 2021 Arifler D, Guillaud M.
europepmc +1 more source