Results 41 to 50 of about 12,386,479 (292)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Towards a south american theory of nuclear development: Nuclear autonomy and regional security
Cadernos Prolam/USPThis article aims to discuss the development of nuclear technology in South America through theoretical lenses that more accurately reflect the observable experiences of the region.
João Marcos Ferreira Pacheco +1 more
doaj +1 more source
Nuclear governance in Latin America
Contexto Internacional, 2013 The article provides an outlook of the regional relations concerning nuclear technology in Latin America. For that purpose, we initially discuss the historic relationship of the Latin American countries with the set of rules, norms, principles and ...
Layla Dawood, Mônica Herz
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The role of Brazil in multilateral disarmament efforts
Revista Brasileira de Política Internacional, 2017 This article examines Brazil’s motivations, objectives, and action in international instances related to nuclear disarmament, non-proliferation, and arms control, particularly the Treaty of Tlatelolco and the Treaty on the Non-proliferation of Nuclear ...
Sérgio de Queiroz Duarte
doaj +1 more source
European Union and the Treaty on the Prohibition of Nuclear Weapons
Akademik İncelemeler Dergisi, 2021 United Nations General Assembly (UNGA) adopted the Treaty on the Prohibition of Nuclear Weapons (TPNW) on July 7, 2017. The Treaty is a legal instrument that highlights the humanitarian aspect of nuclear disarmament and provides an alternative to the ...
Adviye Damla Ünlü
doaj +1 more source
, 2022 Adeliberate effort has been made to identify the core causes and the consequent roots of nuclear proliferation, its related security concerns, and the international response to mitigate the nuclear technology's negative impact, leading to practical solutions.
openaire +2 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
European Union and the Nuclear Weapons Proliferation [PDF]
The Review of International AffairsThe authors explore the driving forces behind the EU’s non-proliferation policies toward existing proliferation cases and crises (India, Pakistan, North Korea, and the Middle East) and answer the question of why the EU’s non-proliferation policy diverges
Marina Kostić Šulejić +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source