Results 31 to 40 of about 69,713 (268)

Assessment of the size of the Khmelnytskyi NPP observation zone taking into account power units No. 5 and 6 with the AP1000 reactor [PDF]

Ядерна фізика та енергетика
An assessment of the size of the observation zone (OZ) of the Khmelnytskyi NPP was carried out, taking into account the potential impact of power units No. 3 and 4 with the VVER-1000 reactor and No.
М. М. Тalerko, Т. D. Lev, А. V. Nosovskyi, V. М. Rudko, А. М. Novikov, O. V. Blokhina   +5 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Solid Oxide Fuel Cell Voltage Prediction by a Data-Driven Approach

Energies
A solid oxide fuel cell (SOFC) is an electrochemical energy conversion device that provides higher thermoelectric efficiency than traditional cogeneration systems. Current research in this field highlights a variety of mathematical models.
Hristo Ivanov Beloev, Stanislav Radikovich Saitov, Antonina Andreevna Filimonova, Natalia Dmitrievna Chichirova, Egor Sergeevich Mayorov, Oleg Evgenievich Babikov, Iliya Krastev Iliev   +6 more
doaj   +1 more source

Criticality of fuel-containing materials in the “Shelter” object [PDF]

Ядерна фізика та енергетика
The article presents the results of the analysis of the validity of simplifications and assumptions accepted by researchers in the models of neutron-physical characteristics of fuel-containing materials (FCM) in the "Shelter" object (SO).
V. I. Borysenko, V. V. Goranchuk, D. I. Khvalin   +2 more
doaj   +1 more source

Improvement of methods for controlling power oil of cooling tower recycling water supply units at Rivne nuclear power plant [PDF]

, 2022
Павло Кузнєцов, Anatolii Tykhomyrov, Olha Biedunkova, Sergey Zaitsev   +3 more
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Environmental and mineralogical studies on the stream sediments of Baltim–El Burullus coastal plain, North Delta, Egypt

Scientific Reports
This work is mainly concerned with the effect of anthropogenic activities and natural radioactivity due to the presence of highly radioactive black sand spots, factory construction, and shipping, in addition to other activities like agriculture on human ...
A. M. Sallam, A. A. Faheim, Z. A. El-Elshafiey, M. M. Abdel Azeem, M. G. El Feky, M. Y. Hanfi   +5 more
doaj   +1 more source