Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Reducing CO2 emissions : nuclear and the alternatives [PDF]
This paper is the second in a series of 8 that make up the evidence base for SDC report 'The role of nuclear power in a low carbon economy'.Publisher ...
Sustainable Development Commission
core +2 more sources
Criteria for Choosing of Resonant Circuit Parameters of Wireless Power Transfer Charging System
The promising element of the infrastructure of unmanned electric vehicles is wireless chargers. The central part of such systems is a resonant circuit that provides wireless power transfer.
V. M. Zavylov +4 more
doaj
Improvement of the method for optimal selection of the type of nuclear reactor [PDF]
The article presents a model for comprehensive assessment and improvement of the comparative analysis method for nuclear reactor types in Ukraine, based on the methods proposed in the KIND and CENESO projects.
A. Nosovskyi +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Assessment of the size of the Khmelnytskyi NPP observation zone taking into account power units No. 5 and 6 with the AP1000 reactor [PDF]
An assessment of the size of the observation zone (OZ) of the Khmelnytskyi NPP was carried out, taking into account the potential impact of power units No. 3 and 4 with the VVER-1000 reactor and No.
М. М. Тalerko +5 more
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Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Solid Oxide Fuel Cell Voltage Prediction by a Data-Driven Approach
A solid oxide fuel cell (SOFC) is an electrochemical energy conversion device that provides higher thermoelectric efficiency than traditional cogeneration systems. Current research in this field highlights a variety of mathematical models.
Hristo Ivanov Beloev +6 more
doaj +1 more source

