Results 41 to 50 of about 40,288 (260)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Criteria for Choosing of Resonant Circuit Parameters of Wireless Power Transfer Charging System

Iranian Journal of Electrical and Electronic Engineering, 2022
The promising element of the infrastructure of unmanned electric vehicles is wireless chargers. The central part of such systems is a resonant circuit that provides wireless power transfer.
V. M. Zavylov, I. Y. Semykina, S. A. Abeidulin, E. A. Dubkov, A. S. Veliliaev   +4 more
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Improvement of the method for optimal selection of the type of nuclear reactor [PDF]

Ядерна фізика та енергетика
The article presents a model for comprehensive assessment and improvement of the comparative analysis method for nuclear reactor types in Ukraine, based on the methods proposed in the KIND and CENESO projects.
A. Nosovskyi, I. Skiter, V. Derengovskyi, V. Rudko   +3 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Assessment of the size of the Khmelnytskyi NPP observation zone taking into account power units No. 5 and 6 with the AP1000 reactor [PDF]

Ядерна фізика та енергетика
An assessment of the size of the observation zone (OZ) of the Khmelnytskyi NPP was carried out, taking into account the potential impact of power units No. 3 and 4 with the VVER-1000 reactor and No.
М. М. Тalerko, Т. D. Lev, А. V. Nosovskyi, V. М. Rudko, А. М. Novikov, O. V. Blokhina   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Environmental and mineralogical studies on the stream sediments of Baltim–El Burullus coastal plain, North Delta, Egypt

Scientific Reports
This work is mainly concerned with the effect of anthropogenic activities and natural radioactivity due to the presence of highly radioactive black sand spots, factory construction, and shipping, in addition to other activities like agriculture on human ...
A. M. Sallam, A. A. Faheim, Z. A. El-Elshafiey, M. M. Abdel Azeem, M. G. El Feky, M. Y. Hanfi   +5 more
doaj   +1 more source