Results 131 to 140 of about 3,625,064 (370)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Nuclear Proliferation

AbstractSupporters of nuclear power expansion resist the notion that nuclear power is connected to nuclear weapons proliferation. However, nuclear power is a necessary precondition, albeit insufficient by itself, for developing nuclear weapons. Plutonium, which is produced by all nuclear reactors in their waste stream, is a primary concern because it ...
Doug Brugge, Aaron Datesman
openaire   +2 more sources

O “Eixo do mal” e a proliferação nuclear

Meridiano 47, 2017
O presente artigo busca analisar o processo de proliferação nuclear, tendo como foco os casos da Coreia do Norte e do Irã.
João Fábio Bertonha
doaj  

Nuclear Autoantigenic Sperm Protein (NASP), a Linker Histone Chaperone That Is Required for Cell Proliferation [PDF]

, 2006
Richard T. Richardson, Oleg Alekseev, Gail Grossman, Esther E. Widgren, Randy Thresher, Eric J. Wagner, Kelly D. Sullivan, William F. Marzluff, Michael G. O’Rand   +8 more
openalex   +1 more source

Civil society legitimacy and nuclear non-proliferation [PDF]

During recent years, civil society legitimacy has generated a growing interest in scholarly research. The present article therefore proposes four normative criteria, namely, independence, transparency, participation, and inclusion, in order to start ...
Kissling, Claudia
core  

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Going, Going, Gone? Assessing Iran's Possible Grounds for Withdrawal from the Treaty on the Non-Proliferation of Nuclear Weapons [PDF]

, 2021
Christopher P. Evans
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Iran's nuclear ambitions and the new world order [PDF]

, 2004
No abstract ...
Mather, Y.
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source