Results 111 to 120 of about 13,104,853 (333)

The modeling of the reaction cross sections in the production of teranositic radionuclides

Nucleus, 2019
We utilize various nuclear reaction codes with the aim to guide, interpret, and support the experiments in the proton-induced production measurements of radionuclides for the development of innovative radio-pharmaceuticals.
Andrea Fontana, Gaia Pupillo, Liliana Mou, Carlos Rossi Alvarez, Juan Esposito, Luciano Canton   +5 more
doaj  

Status of CONRAD, a nuclear reaction analysis tool

, 2007
The development of a software tool (CONRAD) was initiated at CEA/Cadarache to give answers to various problems arising in the data analysis of nuclear reactions. This tool is then characterized by the handling of uncertainties from experimental values to
C. De Saint-Jean, B. Habert, O. Litaize, G. Noguère, C. Suteau   +4 more
semanticscholar   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

GAMMA STRENGTH FUNCTION OF 49Ti BASED ON (n, 2γ) REACTION

Tạp chí Khoa học Đại học Đà Lạt, 2012
Gamma strength functions are important information to study nuclear structure by experiment. The experimental data will check the correctness of the nuclear structure models theory. Nowadays, the comparison between experiment and theory of gamma strength
Nguyễn Đức Hòa
doaj   +1 more source

The Semi-Classical Model for the Nuclear Reaction at Intermediate Energies [PDF]

Progress of Theoretical Physics, 1962
A formalism is presented for the distorted wave approximation for the inelastic scattering of nucleons by nuclei at intermediate energies which lead to the continuous excited states of the residual nucleus. On the a sumption of semi- classical approximation for the disto ted waves of the incoming and outgoing particles, the Tho sFermi model for the ...
openaire   +2 more sources

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Photonuclear reactions in astrophysical p-process: Theoretical calculations and experiment simulation based on ELI-NP

EPJ Web of Conferences, 2017
The astrophysical p-process is an important way of nucleosynthesis to produce the stable and proton-rich nuclei beyond Fe which can not be reached by the s- and r-processes. In the present study, the astrophysical reaction rates of (γ,n), (γ,p), and (γ,α)
Xu Yi, Luo Wen, Balabanski Dimiter, Goriely Stephane, Matei Catalin, Tesileanu Ovidiu   +5 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Our Future Nuclear Data Needs

Annual Review of Nuclear and Particle Science, 2019
A well-established knowledge of nuclear phenomena including fission, reaction cross sections, and structure/decay properties is critical for applications ranging from the design of new reactors to nonproliferation to the production of radioisotopes for ...
L. Bernstein, David A. Brown, A. Koning, B. Rearden, C. Romano, A. Sonzogni, A. Voyles, W. Younes   +7 more
semanticscholar   +1 more source