Results 91 to 100 of about 13,104,853 (333)

Impact of level density models on the calculation of some theranostic radionuclides using EMPIRE code

African Scientific Reports
Radioisotopes such as 67Cu, 131I, and 99mTc are used in nuclear medicine for diagnostic and therapeutic (theranostic) applications. Cross-section data for the nuclear reactions that produce these radioisotopes are essential for efficient production ...
Matthew Inalegwu Amanyi, Umaru Ibrahim, Kolo Matthew   +2 more
doaj   +1 more source

Nuclear astrophysics in the laboratory and in the universe

AIP Advances, 2014
Nuclear processes drive stellar evolution and so nuclear physics, stellar models and observations together allow us to describe the inner workings of stars and their life stories.
A. E. Champagne, C. Iliadis, R. Longland
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Demo 25-15 Mousetrap Chain Reaction

, 2001
An array of mousetraps, each loaded with two Ping-Pong balls, is used as the classic model of an uncontrolled nuclear chain reaction, as seen in Figure 1 just as the device is fired.

core  

Neutrino Interactions Importance to Nuclear Physics [PDF]

, 2009
We review the general interplay between Nuclear Physics and neutrino-nucleus cross sections at intermediate and high energies. The effects of different reaction mechanisms over the neutrino observables are illustrated with examples in calculations using ...
J. Nieves, Barbaro, M. B., M. Sorel, J. M. Udias, Caballero Carretero, Juan Antonio, Udias, J. M., M. Valverde, C. Maieron, Luis Alvarez-Ruso, Federico Sanchez, Donnelly, T. W., T. W. Donnelly, Maieron, C., Nieves, J., Amaro, J. E. (Coordinador), Valverde, M., J. E. Amaro, M. B. Barbaro, J. A. Caballero, Amaro, J. E.   +19 more
core   +1 more source

Silicon Isotopic Composition of Mainstream Presolar SiC Grains Revisited: The Impact of Nuclear Reaction Rate Uncertainties

The Astrophysical Journal Letters
Presolar grains are stardust particles that condensed in the ejecta or in the outflows of dying stars and can today be extracted from meteorites. They recorded the nucleosynthetic fingerprint of their parent stars and thus serve as valuable probes of ...
Hung Kwan Fok, Marco Pignatari, Benoît Côté, Reto Trappitsch   +3 more
doaj   +1 more source

Short-range correlations in dynamical intranuclear cascade models for describing nucleon knockout reactions

Physics Letters B
Spallation and fragmentation reactions at incident energies above the Fermi momentum are considered to be the main mechanism for the production of neutron-rich nuclei at worldwide nuclear physics facilities, such as RIBF, FRIB, and GSI-FAIR.
J.L. Rodríguez-Sánchez, J. Cugnon, J.C. David, J. Hirtz   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The multichannel experimental and theoretical study of the 12C(18O,18F)12B single charge exchange reaction mechanism

, 2023
The study of a network of nuclear reactions populated in the 18O + 12C collision is the main topic of the present paper. It was performed to test nuclear structure and reaction theories in describing the full reaction mechanism occurring in the (18O, 18F)
Gargano A., Souliotis G. A., Finocchiaro P., Spatafora A., Linares R., Djapo H., Borello-Lewin T., Ciraldo I., Pakou A., Medina N., De Gregorio G., Zagatto V. A. B., Agodi C., Lubian J., Solakci S. O., Lay J. A., Da Silveira M. -C. A. G., Fisichella M., Chavez-Lomeli E. R., Cavallaro M., Torresi D., Tudisco S., Carbone D., Delaunay F., Amador-Valenzuela P., Oliveira J. R. B., Hacisalihoglu A., Calvo D., Soukeras V., Firat S., Sgouros O., Petrascu H., Acosta L. E., Eke C., Cappuzzello F., Yildirim A., Brischetto G. A., Moralles M., Pandola L.   +38 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source