Results 71 to 80 of about 354,049 (298)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Cross-section Calculations of 175Lu(n,p)175Yb reaction for production of medically important radioisotope 175Yb [PDF]

EPJ Web of Conferences
Ytterbium-175 (175Yb) is considered suitable for the preparation of therapeutic radiopharmaceuticals due to its decay characteristics (T1/2 = 4.18 d).
Nadeem Muhammad, Hameed Qaiser Syed, Mahmood Tayyab, Muhammad Atta, Sajjad Muhammad   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Nuclear data for the thorium fuel cycle and the transmutation of nuclear waste [PDF]

, 2016
Neutron-induced reaction cross sections play an important role in a wide variety of research fields, ranging from stellar nucleosynthesis, the investigation of nuclear level density studies, to applications of nuclear technology, including the ...
Calviño Tavares, Francisco, Cortés Rossell, Guillem Pere, Gunsing, Frank, Altstadt, Sebastian, Andrzejewski, Józef   +4 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Transitions To Door-way States And Nuclear Responses Against 2-body External Fields [PDF]

EPJ Web of Conferences
Nuclear microscopic structural models that treat two-body effective interactions self-consistently becomes available, one of which is second-random-phase-approximation (SRPA).
Minato Futoshi
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Nuclear astrophysics in the laboratory and in the universe

AIP Advances, 2014
Nuclear processes drive stellar evolution and so nuclear physics, stellar models and observations together allow us to describe the inner workings of stars and their life stories.
A. E. Champagne, C. Iliadis, R. Longland
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Short-range correlations in dynamical intranuclear cascade models for describing nucleon knockout reactions

Physics Letters B
Spallation and fragmentation reactions at incident energies above the Fermi momentum are considered to be the main mechanism for the production of neutron-rich nuclei at worldwide nuclear physics facilities, such as RIBF, FRIB, and GSI-FAIR.
J.L. Rodríguez-Sánchez, J. Cugnon, J.C. David, J. Hirtz   +3 more
doaj   +1 more source