Results 31 to 40 of about 545,425 (311)

Diverse and Flexible Coping Strategy for Nuclear Safety: Opportunities and Challenges

open access: yes, 2022
The concept and methodology of traditional Defense in Depth (DID) was challenged in the Fukushima nuclear accident. In order to fix the weakness of the traditional emergency strategies of nuclear power plants (NPPs) and to enhance the DID for nuclear ...
Hong Xu, Baorui Zhang
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Activation analysis of targets and lead in a lead slowing down spectrometer system

open access: yesNuclear Engineering and Technology, 2018
A neutron generation system was developed to induce fissile fission in a lead slowing down spectrometer (LSDS) system. The source neutron is one of the key factors for LSDS system work.
Yongdeok Lee   +3 more
doaj   +1 more source

The EU and Iran’s Nuclear Programme: Testing the Limits of Coercive Diplomacy. College of Europe EU Diplomacy Paper 1/2009 [PDF]

open access: yes, 2009
The paper analyzes the E-3’s/EU’s diplomatic strategy vis-à-vis Iran and its nuclear programme against the theoretical background of coercive diplomacy.
Tocha, Monika.
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Fuel Mass Transfer in Single-cell Thermionic Fuel Element and Its Influence on Fuel Performance

open access: yesYuanzineng kexue jishu, 2023
With a compact structure, static thermoelectric conversion can be achieved by the single-cell thermionic fuel element (single-cell TFE), which shows obvious technical advantages and broad application prospects.
LEI Huazhen;ZHONG Wuye;JIANG Wei;ZHAO Zhenhua
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Nuclear-armed submarines in Indo-Pacific Asia: stabiliser or menace? [PDF]

open access: yes, 2015
This report examines the implications of sea-based nuclear weapons for strategic stability in the Indo-Pacific. This paper is part of a wider research and outreach project on nuclear stability in a changing Indo-Pacific Asia, supported by a grant from ...
Brendan Thomas-Noone, Rory Medcalf
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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