Results 51 to 60 of about 545,425 (311)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A perfect match: Nuclear energy and the National Energy Strategy

open access: yes, 1990
In the course of developing the National Energy Strategy, the Department of Energy held 15 public hearings, heard from more than 375 witnesses and received more than 1000 written comments.

core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The Trump Administration’s Nuclear Posture Review (NPR): In Historical Perspective

open access: yesJournal for Peace and Nuclear Disarmament, 2018
Except for the Eisenhower administration’s threat of nuclear retaliation to even local non-nuclear and limited aggression, the Trump administration’s Nuclear Posture Review (NPR) is the most open description of US capabilities and strategies for ...
Seyom Brown
doaj   +1 more source

Talking Away the Crisis? The E3/EU-Iran Negotiations on Nuclear Issues. College of Europe EU Diplomacy Paper 6/2007, November 2007 [PDF]

open access: yes, 2007
The E3/EU-Iran negotiations on nuclear issues have been ongoing since summer 2003 with the aim to find a balance between Iran’s desire to establish a peaceful nuclear enrichment programme and satisfying the safeguards of the international community ...
Roudsari, Sahar Arfazadeh.
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The Iranian Nuclear Program

open access: yesCzech Journal of International Relations, 2011
Using the empirical case of the Iranian nuclear program, the presented text is intended to test and conceptualize the security model of nuclear weapons proliferation, as it was outlined by Scott Sagan.
Jan Ludvík
doaj  

From Nuclear Hedging to Korea-Japan Nuclear Weapons Free Zone: Japan's Nuclear Options

open access: yesThe Copenhagen Journal of Asian Studies, 2016
This article discusses both the positive and negative effects of Japan's three nuclear strategies: nuclear hedging, nuclear breakout, and the Korea-Japan Nuclear Weapons Free Zone (KJNWFZ).
Tianjiao Jiang
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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