Results 41 to 50 of about 1,272,933 (303)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Analysis on Improving Utilization of Uranium Resource Based on Fast Reactor with Closed Fuel Cycle

Yuanzineng kexue jishu, 2023
Fast reactor combined with closed fuel cycle can greatly improve the utilization rate of uranium resource, get rid of the dependence of nuclear energy development on natural uranium, and meanwhile, reduce the generation of long-lived radioactive waste ...
HU Yun;YANG Yong;SONG Yingyun;YANG Peng
doaj  

WHETHER ASIA IS EXPOSED TO NUCLEAR CONFLICT

Security and Defence Quarterly, 2016
The analysis of the political-military situation in South-east Asia shows that it is a hot spot area which, in the future, might be a place of nuclear conflict.
Stanisław ZARYCHTA
doaj   +1 more source

MIMAC : A micro-tpc matrix for directional detection of dark matter

, 2010
Directional detection of non-baryonic Dark Matter is a promising search strategy for discriminating WIMP events from background. However, this strategy requires both a precise measurement of the energy down to a few keV and 3D reconstruction of tracks ...
A Delbart, Ahlen S, Aprile E, C Golabek, C Grignon, Ch Fourel, D Santos, E Ferrer, F J Iguaz, F Mayet, G Bosson, Grignon C, I Giomataris, J Billard, J L Bouly, J P Mols, J P Richer, L Lebreton, Moulin E, O Bourrion, O Guillaudin, Santos D, Santos D   +22 more
core   +8 more sources

In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors. [PDF]

, 2016
Aberrant Hedgehog (Hh)/glioma-associated oncogene (GLI) signaling has been implicated in cancer progression. Here, we analyzed GLI1, Sonic Hedgehog (Shh) and NF-κB expression in 51 breast cancer (ductal carcinoma) tissues using immunohistochemistry ...
Bei, R., Benvenuto, M, Bonanno, E, Cucchi, Danilo, DE SMAELE, Enrico, DI STEFANO, Enrica, Fantini, M, Frajese, Gv, Gulino, Alberto, Masuelli, Laura, Mattera, Rosanna, Modesti, A, Orlandi, A, Screpanti, Isabella   +13 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Nuclear Strategy of the DPRK in Modern Conditions

Journal for Peace and Nuclear Disarmament
The global shifts of recent years have not bypassed Northeast Asia, increasing the conflict potential of the region as a whole and the Korean peninsula in particular.
Anastasia Barannikova
doaj   +1 more source

Semihard Interactions in Nuclear Collisions Based on a Unified Approach to High Energy Scattering [PDF]

, 1998
Our ultimate goal is the construction of a model for interactions of two nuclei in the energy range between several tens of GeV up to several TeV per nucleon in the centre-of-mass system.
Drescher, H. J., Hladik, M., Ostapchenko, S., Werner, K.   +3 more
core   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source