Results 91 to 100 of about 522,946 (185)

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Non-strategic nuclear weapons: the next step in multilateral arms control [PDF]

open access: yes
This paper by Crispin Rovere and Kalman A Robertson addresses the many barriers to including tactical nuclear weapons in disarmament talks. It considers the difficulty of bringing other emerging powers such as China into the nuclear arms control equation.
Crispin Rovere, Kalman A Robertson
core  

Otto Hahn und die Kaiser-Wilhelm-Gesellschaft im Zerrspiegel neuerer Kritik [PDF]

open access: yes, 2006
In recent publications Otto Hahn, last president of the Kaiser-Wilhelm-Gesellschaft, is charged with having favoured the Nazi regime, before World War II by politically purging institutes and suppressing Lise Meitner’s contribution to the discovery of ...
Trömel, Martin
core  

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

From old wars to new wars and global terrorism [PDF]

open access: yesarXiv, 2005
Even before 9/11 there were claims that the nature of war had changed fundamentally. The 9/11 attacks created an urgent need to understand contemporary wars and their relationship to older conventional and terrorist wars, both of which exhibit remarkable regularities.
arxiv  

Perdamaian dan Profesi Kedokteran [PDF]

open access: yes, 1986
: R. Soewasono . Peace and the medical profession This article described how nuclear weapons could pose a threat to the health and life of people. An all out nuclear war would destroy world civilization, and human existence itself would be imperiled ...
R. Soewasono
core   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Nuclear threats, nuclear deterrence, and the future of nuclear restraint regimes after Russia's war of aggression [PDF]

open access: yes
Russia's war of aggression exacerbates nuclear threats in multifaceted and potentially catastrophic ways, while diminishing the prospects for arms control and nuclear restraint regimes. In this, it is comparable to the early phases of the Cold War.
Dembinski, Matthias, Polianskii, Mikhail
core   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

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