Results 91 to 100 of about 470,414 (263)

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Global Boiling by Nuclear Heated Ocean: Unstoppable Atomic Generations [PDF]

open access: yes, 2014
Hiroyuki Itsuki has said that Fukushima was a ‘second war defeat’. Japan, which suffered the atomic bombing of ‘Hiroshima’ and ‘Nagasaki’ in the Second World War, wasonce again visited by a nuclear incident at Fukushima.
Atsuji Shigeo   +3 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

BUFFER ZONE IN INDONESIAN TERRITORY TO ANTICIPATE IMPACTS OF NUCLEAR WAR ON KOREAN PENINSULA [PDF]

open access: yesJournal of Defense Resources Management
The nuclear issue on the Korean Peninsula in recent decades is considered to have become one of the serious threats to security and stability in East Asia in particular and the world in general.
Riko FENDIAWAN   +3 more
doaj  

War of the Worlds Revisited: The Effect of Watching The Day After on Mood State [PDF]

open access: yes, 2011
In the fall of 1983, The Day After, a fictional account of a nuclear attack on a civilian population, was broadcast on television in the United States and viewed by I00 million Americans .
Daniel, MD, David G.   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Vulcan Survivability in Nuclear War

open access: yesAir and Space Power Review, 2023
Post the Royal Air Force’s nuclear deterrent role, and the end of Britain’s V-bomber force, several academic papers have questioned the ability of the V-force to survive long enough over the Soviet Union to release its nuclear weapons onto its Supreme ...
Julian Grenfell
doaj  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Review of Golem: Modern Wars and Their Monsters by Maya Barzilai

open access: yes, 2018
The golem crosses many borders. A popular culture icon and an enduring image of creative power, its hybridity contributes to its elusive nature. What it is and what it means shifts over time. Maya Barzilai\u27s Golem: Modern Wars and Their Monsters takes
Berg, Temma F.
core  

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