Results 71 to 80 of about 467,386 (232)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Trump Administration’s Nuclear Posture Review (NPR): In Historical Perspective
Except for the Eisenhower administration’s threat of nuclear retaliation to even local non-nuclear and limited aggression, the Trump administration’s Nuclear Posture Review (NPR) is the most open description of US capabilities and strategies for ...
Seyom Brown
doaj +1 more source
Clinical Sociology and Preventing Nuclear War [PDF]
This paper outlines major kinds of social science research, especially sociological, that have relevance for nuclear war prevention and that would be relevant to a variety of clients. Research that has been done as well as work that could be done to help
Kriesberg, Louis
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The Russia-Ukraine War and Nuclear Weapons: Evaluating Familiar Insights
This article examines the nuclear dimension of the war in Ukraine. It makes two arguments. First, our knowledge of the nuclear world is fundamentally limited and so any inferences we draw from the war in Ukraine should be tentative.
Mark S. Bell
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Book review: understanding the imaginary war: culture, thought and nuclear conflict, 1945-90 edited by Matthew Grant and Benjamin Ziemann [PDF]
In Understanding the Imaginary War: Culture, Thought and Nuclear Conflict, 1945-90, editors Matthew Grant and Benjamin Ziemann offer a collection focusing on how the unknowable and inconceivable – nuclear war – was necessarily imagined during the Cold ...
Curtis, April
core
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
DEVOTED ACTOR VERSUS RATIONAL ACTOR MODELS FOR UNDERSTANDING WORLD CONFLICT Presented To The National Security Council At The White House, September 14, 2006 [PDF]
Ever since the end of the Second World War, Rational Actor models have dominated strategic thinking at all levels of government policy and military planning.
Scott Atran
core

