Results 61 to 70 of about 467,386 (232)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A Tough Little Boat: The Pogo-HMCS Labrador’s Hydrographic Survey Launch [PDF]
, 2012 In the summer of 1995 the Canadian War Museum accepted delivery of the Pogo, the 36-foot aluminum sounding boat which had accompanied the voyages of HMCS Labrador, Canada’s first and last Arctic Patrol vessel.
Fernberg, Eric
core +1 more source
In Pursuit of a Grand Strategy: An Explanation of Pakistan’s Evolving Nuclear Policy [PDF]
, 2008 Explaining, investigating and analysing South Asian security scene in the post-Cold War takes into account overt nuclearisation by India and Pakistan in 1998 and the changing perceptions and requirements of national security as reflected in the policy ...
Alam, Mohammed Badrul
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Nuclear Imminence in Contemporary Indo‐Pakistani Conflict [PDF]
, 2009 November of 2008 saw frightening attacks on India’s foreigners. Over the course of three days, hostages had been taken, hotels and restaurants in India’s busiest city of Mumbai were burned and English, American and Canadian citizens lay among the nearly ...
Tobin, Anna K.
core
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source