Results 41 to 50 of about 470,414 (263)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
"A Flame that is Burning the World": Edwin Muir, war, and history [PDF]
, 2016 Discusses the impact of successive wars on the Scottish poet, translator and critic Edwin Muir (1887-1959), with especial focus on his experiences in post-World War II Prague and his response to the threat of nuclear warfare and human ...
Palmer McCulloch, Margery
core +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
In Pursuit of a Grand Strategy: An Explanation of Pakistan’s Evolving Nuclear Policy [PDF]
, 2008 Explaining, investigating and analysing South Asian security scene in the post-Cold War takes into account overt nuclearisation by India and Pakistan in 1998 and the changing perceptions and requirements of national security as reflected in the policy ...
Alam, Mohammed Badrul
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A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
The Russia-Ukraine War and Nuclear Weapons: Evaluating Familiar Insights
Journal for Peace and Nuclear DisarmamentThis article examines the nuclear dimension of the war in Ukraine. It makes two arguments. First, our knowledge of the nuclear world is fundamentally limited and so any inferences we draw from the war in Ukraine should be tentative.
Mark S. Bell
doaj +1 more source
Journal for Peace and Nuclear Disarmament, 2022 Will emerging technology increase the possibility of nuclear war? Given the multitude of ways emerging technology intersects with nuclear weapons, critical thinking about an imagined future that goes beyond net assessment, myopic mirror-imaging, and ...
James Johnson
doaj +1 more source
Letter from Joan Cook, Church and Society Commission of the National Council of Churches in New Zealand, to Geraldine Ferraro [PDF]
, 1984 Letter from Joan Cook, acting secretary of the Church and Society Commission of the National Council of Churches in New Zealand, to Geraldine Ferraro.
Cook, Joan, Ferraro, Geraldine
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“The hope – the one hope – is that your generation will prove wiser and more responsible than mine.” Constructions of guilt in a selection of disaster texts for young adults [PDF]
, 2012 This paper explores a range of definitions of guilt, and argues that fiction for young adults which is set after a major disaster that has been caused by humans has surprisingly little emphasis on guilt.
Baccolini +26 more
core +3 more sources