Results 181 to 190 of about 622 (258)

Prostaglandin D2 Synthase Controls Schwann Cells Metabolism and Peripheral Myelin Homeostasis

Glia, Volume 74, Issue 3, March 2026.
Prostaglandin D2 Synthase (L‐PGDS) controls PPNS myelin lipids’ composition and Schwann cells energetic metabolism In the absence of L‐PGDS Schwann cells turn to acetate as the main energetic source. These metabolic changes result in ketone bodies production to preserve neuronal survival.
Amelia Trimarco, Matteo Audano, Rosa La Marca, Marta Pellegatta, Paolo Canevazzi, Mariaconcetta Cariello, Marta Falco, Silvia Pedretti, Gabriele Imperato, Alessandro Cestaro, Paola Podini, Giorgia Dina, Angelo Quattrini, Luca Massimino, Donatella Caruso, Nico Mitro, Carla Taveggia   +16 more
wiley   +1 more source

Electrically-driven phase transition actuators to power soft robot designs. [PDF]

Nat Commun
Fonseca D, Neto P.
europepmc   +1 more source

Engineered CAR‐T–Derived Exosomes Co‐Delivering miR‐145 and Cytotoxic Proteins for Targeted Solid Tumour Therapy

Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
ABSTRACT Chimeric antigen receptor T cell (CAR‐T) therapy has demonstrated remarkable efficacy in haematologic malignancies but remains constrained in solid tumours due to limited tumour penetration, immunosuppressive microenvironments and the risk of cytokine release syndrome (CRS).
Ruyue Yang, Haitao Wang, Guidan Wang, Gankun Yuan, Zhaoyi Wei, Junling An, Dong Hu, Wenjing Wen, Shegan Gao, Yuan Wan, Gaofeng Liang   +10 more
wiley   +1 more source

Modeling corium pool stratification and focusing effect in APR1400 using a multiphase CFD framework. [PDF]

Sci Rep
Mahboob K, Alkaabi A, Addad Y.
europepmc   +1 more source

Neuronal Extracellular Vesicles Carrying APOE Downregulate Filament Actin Polymerization Signaling to Inhibit Synapse Formation in Alzheimer's Disease

Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
During AD progression, EVs derived from APP/PS1 neurons transport APOE into healthy neurons, potentially interacting with neuronal APOE receptors (LRP1, LDLR, VLDLR) to transduction the signaling. This signaling inhibits Rac1‐GTP activation and subsequently downregulates F‐actin polymerization through the Rac1‐N‐WASP‐Arp2/3 pathway.
Yang Yu, Zhixin Ma, Taixu Li, Wenjun Xiao, Zhigang Li   +4 more
wiley   +1 more source

N‐Acetylglucosamine Selectively Attenuates Neuroinflammation in a Mouse Model of Mitochondrial Dysfunction

Acta Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim Mitochondrial dysfunction plays a central role in multiple neurodegenerative diseases, yet the temporal sequence of cellular events underlying neurodegeneration remains poorly defined. This study aimed to characterize the progression of neurodegeneration in a mouse model of fatal mitochondrial encephalopathy and to evaluate the therapeutic
Laura Jiménez‐Sánchez, Paula Ruiz‐López, Pilar González‐García, Janne Purhonen, Juan Manuel Martínez‐Gálvez, Sergio López‐Herrador, Julia Corral‐Sarasa, María Elena Díaz‐Casado, Carmen Venegas, Isaac Santos‐Pérez, Enrica Olivieri, Adriana L. Rojas, Luis Carlos López   +12 more
wiley   +1 more source

Aerogel-based Leidenfrost vapor percolator for ultra-fast thermal cooling. [PDF]

Nat Commun
Wang H, Xu Y, Li P, Liu Q, Cheng L, Yu J, Si Y.   +6 more
europepmc   +1 more source

A Model‐Based Interpretation for the Apparently Homogeneous Steam Bubble Nucleation in Industrial Evaporative Sucrose Crystallization

Journal of Food Process Engineering, Volume 49, Issue 3, March 2026.
A model has been developed and validated with data from the sugar industry to determine the evaporation rate of discontinuous evaporating crystallizers. The results indicate that vapor nucleation on the surface of sucrose crystals is a significant factor, particularly in the context of low temperature differences in the calandria.
Felix Geisendörfer, Eckhard Flöter, João Henrique Faller Moura   +2 more
wiley   +1 more source

The Rhus chinensis Genome Provides Insights Into Tannin, Flavonoid Biosynthesis, and Glandular Trichome Development

Plant Biotechnology Journal, Volume 24, Issue 3, Page 988-1013, March 2026.
ABSTRACT The “salt tree”, Rhus chinensis, holds significant economic and medicinal value due to its ability to produce Galla chinensis (Chinese gall/gallnut), a plant‐derived medicinal material used in both traditional Chinese and modern medicine that is rich in tannins and flavonoids. It is also renowned for its remarkable stress tolerance.
Zhaogeng Lu, Helin Zou, Jiawen Cui, Tongfei Wang, Lingyu Ma, Shixiong Ren, Yiwei Cao, Xi Zhang, Zixi Chen, Hongyan Bao, Ling Zhu, Yaning Cui, Ruili Li, Xiuyan Yang, Qikun Zhang, Zhili Wang, Wangxiang Zhang, Li Wang, Jinxing Lin, Biao Jin   +19 more
wiley   +1 more source

BolAG‐BolRPI2‐BolBAM4 Module Regulates the Bolting of Curd by Modulating Starch Metabolism in Broccoli (Brassica oleracea var. italica)

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1465-1481, March 2026.
ABSTRACT The curd is a unique indeterminate inflorescence structure, which is the most important edible organ of broccoli. Premature bolting of the curd is a major factor that limits the yield and marketability of broccoli. However, the formation and development of broccoli curd, especially the bolting of curd, remain poorly understood.
Yinxia Zhu, Mengwei Xi, Yuxuan Duan, Hanmin Jiang, Jingjing Xie, Mengyao Zhao, Ce Liu, Hui Li, Chunguo Wang   +8 more
wiley   +1 more source