Results 51 to 60 of about 622 (258)

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

open access: yesAdvanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun   +11 more
wiley   +1 more source

Nucleate Pool Boiling Heat Transfer Characteristics of Refrigerant/Oil Mixture with Carbon Nanotubes

open access: yesZhileng xuebao, 2011
Influence of carbon nanotubes (CNTs) on nucleate pool boiling heat transfer characteristics of refrigerant-oil mixture was investigated experimentally. Four types of CNTs with the outside diameters from 15 nm to 80 nm and the lengths from 1.5 μm to 10 μm
Zhuang Dawei   +4 more
doaj  

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

open access: yesAdvanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun   +5 more
wiley   +1 more source

Pool nucleate boiling of water on sintered surface by laser type metal 3D printing

open access: yesNihon Kikai Gakkai ronbunshu, 2019
An experimental study is currently being carried out to reveal the effects of the laser power for sintering on the cavity formation of a sintered test piece, and on the pool saturation boiling of deionized water under atmospheric pressure. The test piece
Hidemi TOH   +4 more
doaj   +1 more source

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

open access: yesAdvanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li   +10 more
wiley   +1 more source

Nucleate Pool Boiling Heat Transfer from High-Flux Tube with Dielectric Fluid HFE-7200

open access: yesEnergies, 2020
In the present experimental study, nucleate pool boiling heat transfer measurements of two high-flux tubes (sample A and sample B) were conducted at atmospheric pressure with HFE-7200 as the working fluid.
Abhishek Kumar   +2 more
doaj   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

open access: yesAdvanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li   +12 more
wiley   +1 more source

Intracellular Aβ42 Sequestration by a Serine Protease Mitigates Neurotoxicity in a Drosophila Alzheimer's Disease Model

open access: yesAdvanced Science, EarlyView.
Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su   +4 more
wiley   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

open access: yesAdvanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan   +20 more
wiley   +1 more source

Pool boiling on rectangular fins with tunnel-pore structure

open access: yesEPJ Web of Conferences, 2013
Complex experimental investigations were conducted in the area of pool boiling heat transfer on extended surfaces with internal tunnels limited by perforated foil. The experiments were carried out for water and R-123 at atmospheric pressure.
Pastuszko A.
doaj   +1 more source

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