Results 71 to 80 of about 8,087 (328)

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

open access: yesAdvanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu   +16 more
wiley   +1 more source

Nucleate Pool Boiling Heat Transfer from High-Flux Tube with Dielectric Fluid HFE-7200

open access: yesEnergies, 2020
In the present experimental study, nucleate pool boiling heat transfer measurements of two high-flux tubes (sample A and sample B) were conducted at atmospheric pressure with HFE-7200 as the working fluid.
Abhishek Kumar   +2 more
doaj   +1 more source

Nucleate pool boiling in the long duration low gravity environment of the Space Shuttle [PDF]

open access: yes
The results are presented of an experimental study of nucleate pool boiling performed in the low gravity environment of the space shuttle. Photographic observations of pool boiling in Freon 113 were obtained during the 'Tank Pressure Control Experiment,'
Bentz, M. D.   +4 more
core   +1 more source

Simulation and experimental investigation of pool boiling on a silicon wafer with artificial nucleation sites [PDF]

open access: yes, 2008
This paper reports progress on a project to develop a design tool for large arrays of nucleation sites at specified locations to achieve high rates of cooling by pool boiling. The tool will be based on an improved version of a hybrid simulation, in which
Golobic, I   +9 more
core  

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

open access: yesAdvanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu   +15 more
wiley   +1 more source

Nucleate pool boiling investigation on a silicon test section with micro-fabricated cavities [PDF]

open access: yes, 2009
The basic mechanisms of nucleate boiling are still not completely understood, in spite of the many numerical and experimental studies dedicated to the topic.
Hutter, C   +5 more
core  

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

open access: yesAdvanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu   +10 more
wiley   +1 more source

Flow boiling in a 1.1mm tube with R134a: Experimental results and comparison with model [PDF]

open access: yes, 2007
A detailed comparison of the three-zone evaporation model, proposed by Thome et al. (2004), with experimental heat transfer results of two stainless steel tubes of internal diameter 4.26 mm and 2.01 mm using R134a fluid was presented by Shiferaw et al ...
Karayiannis, TG   +2 more
core   +1 more source

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

open access: yesAdvanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang   +7 more
wiley   +1 more source

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