Results 191 to 200 of about 6,071,343 (411)

Recent advances and perspectives of nucleic acid detection for coronavirus

Journal of Pharmaceutical Analysis, 2020
Minzhe Shen, Ying Zhou, Jiawei Ye, Abdu Ahmed Abdullah Al-Maskri, Yu Kang, S. Zeng, Sheng Cai   +6 more
semanticscholar   +1 more source

Encapsulation of Small Extracellular Vesicles into Selectively Disassemblable Shells of PEGylated Metal‐Phenolic Networks

Advanced Healthcare Materials, EarlyView.
Small extracellular vesicles (sEVs) are encapsulated into protective shells composed of metal‐phenolic networks (MPNs) and secondary poly(ethylene glycol) layers. This surface modification approach enhances the storage stability of sEVs while maintaining their integrity and functionality. The shells can be selectively disassembled under mild conditions.
Chenyu Wang, Ailifeire Fulati, Kenta Kimura, Xianglan Li, Joseph J. Richardson, Mitsuru Naito, Kanjiro Miyata, Takanori Ichiki, Hirotaka Ejima   +8 more
wiley   +1 more source

A Spectrophotometric Study on the Deoxypentose Nucleic Acid - Cysteine Reaction. [PDF]

, 1953
Sam Brody, O. Fernö, H. Fex, Björn Högberg, T. Linderot, Th. Rosenberg   +5 more
openalex   +1 more source

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

Science, 2018
J. Gootenberg, Omar O. Abudayyeh, M. Kellner, J. Joung, J. Collins, Feng Zhang   +5 more
semanticscholar   +1 more source

Engineered Chitosan‐Derived Nanocarrier for Efficient siRNA Delivery to Peripheral and Central Neurons

Advanced Healthcare Materials, EarlyView.
This study introduces a novel chitosan‐based nanocarrier functionalized with a neurotropic protein for efficient siRNA delivery to neurons. The polyplexes demonstrate enhanced neuronal binding, retrograde transport, and PTEN silencing, promoting axonal outgrowth.
Ana P. Spencer, Adriana Vilaça, Miguel Xavier, Rafael Santos, Ariel Ionescu, María Lázaro, Victoria Leiro, Eran Perlson, Sofia C. Guimarães, Ben M. Maoz, Ana P. Pêgo   +10 more
wiley   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

Advanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan, Jonathan James Stanley Rickard, Mark Robert Thomas, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source

Low-density lipoprotein receptor-related protein 2 (LRP2) is required for lipid export in the midgut of the migratory locust, Locusta migratoria

Journal of Integrative Agriculture
Low-density lipoprotein receptor-related protein 2 (LRP2) is a multifunctional endocytic receptor expressed in epithelial cells. In mammals, it acts as an endocytic receptor that mediates the cellular uptake of cholesterol-containing apolipoproteins to ...
Yiyan Zhao, Weimin Liu, Xiaoming Zhao, Zhitao Yu, Hongfang Guo, Yang Yang, Hans Merzendorfer, Kun Yan Zhu, Jianzhen Zhang   +8 more
doaj  

Corrigendum: Receptor of advanced glycation end products deficiency attenuates cisplatin-induced acute nephrotoxicity by inhibiting apoptosis, inflammation and restoring fatty acid oxidation

Frontiers in Pharmacology, 2022
Qiang Wang, Qiang Wang, Yuemei Xi, Yuemei Xi, Binyang Chen, Binyang Chen, Hairong Zhao, Hairong Zhao, Wei Yu, Wei Yu, De Xie, De Xie, Weidong Liu, Weidong Liu, Furong He, Furong He, Chenxi Xu, Chenxi Xu, Jidong Cheng, Jidong Cheng   +19 more
doaj   +1 more source

Topological Machine Learning for Protein-Nucleic Acid Binding Affinity Changes Upon Mutation [PDF]

arXiv
Understanding how protein mutations affect protein-nucleic acid binding is critical for unraveling disease mechanisms and advancing therapies. Current experimental approaches are laborious, and computational methods remain limited in accuracy. To address this challenge, we propose a novel topological machine learning model (TopoML) combining persistent
arxiv  

STUDIES IN HISTOCHEMISTRY: I. DETERMINATION OF NUCLEIC ACIDS IN MICROGRAM AMOUNTS OF TISSUE [PDF]

, 1956
Jesse F. Scott, ALBA P. FRACCASTORO, Edgar B. Taft   +2 more
openalex   +1 more source