Results 181 to 190 of about 210,426 (263)

Development of isothermal nucleic acid amplification technologies for rapid detection of Porcine Enterovirus-G. [PDF]

PLoS One
Kaushik S, Maan S, Batra K, Sindhu S, Kadian V, Kumar A.   +5 more
europepmc   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

Low-complexity automated nucleic acid amplification tests for extrapulmonary tuberculosis and rifampicin resistance in adults and adolescents. [PDF]

Cochrane Database Syst Rev
Kohli M, Inbaraj LR, Salomon A, Scandrett K, Korobitsyn A, Ismail N, Srinivasalu VA, Daniel J, Steingart KR, Takwoingi Y.   +9 more
europepmc   +1 more source

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

Advanced Science, EarlyView.
The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu, Jiaheng Lin, Yifei Zhu, Ying Liu, Guoren Zhou   +4 more
wiley   +1 more source

Raman Analysis of RNA Nucleotide Strands From SARS‐CoV‐2 Variants and Subvariants: A Step Forward in the Definition of “Raman Genome”

Advanced Science, EarlyView.
Main Raman signals in RNA, related to helical backbone, ribofuranose ring, and nitrogenous bases, are affected by secondary structures that cause hyperchromic effects and significantly alter the Raman intensity. ABSTRACT Raman spectra of RNA nucleotide strands extracted from 20 SARS‐CoV‐2 strains, including the original Japanese isolate, Alpha, Beta ...
Giuseppe Pezzotti, Yoshiki Yasukochi, Gianluca Angiola, Takaharu Ueno, Saki Ikegami, Rintaro Okawa, Tetsuya Adachi, Wenliang Zhu, Osam Mazda, Alfio Grillo, Koichiro Higasa, Kazu Okuma   +11 more
wiley   +1 more source

STI prevalence and the integration of point-of-care nucleic acid amplification testing into STI diagnostic algorithms at a Médecins Sans Frontières key population clinic in San Pedro Sula, Honduras. [PDF]

Front Reprod Health
Johnson DC, Rodriguez K, Gómez-López D, Rodríguez D, Dávila D, Salem-Bango L, Guinart Verdaguer J, Perotti C, Ortuño Gutiérrez R, Staderini N, Ciglenecki I.   +10 more
europepmc   +1 more source

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

Advanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li, Xi Wan, Xinru Su, Zechuan Li, Yue Wang, Ying Wang, Ruofei Li, Huangzhao Wei, Jianbin Zhang, Shuai Wang   +9 more
wiley   +1 more source

Chemotherapy and anti-CD20 monoclonal antibody impact on SARS-CoV-2 nucleic acid amplification tests in hematologic malignancies: a retrospective study. [PDF]

BMC Infect Dis
Kinoshita K, Maruyama W, Miyake H, Sada RM.   +3 more
europepmc   +1 more source

Novel isothermal nucleic acid amplification method for detecting malaria parasites. [PDF]

Appl Microbiol Biotechnol
de Queiroz LT, Baptista BO, de Abreu-Fernandes R, Pereira CSF, Lemos JAS, de Souza HADS, Martorano RM, Riccio EKP, Totino PRR, Oliveira-Ferreira J, Lima-Junior JDC, Daniel-Ribeiro CT, Pratt-Riccio LR.   +12 more
europepmc   +1 more source

Recombinase-Controlled Multiphase Condensates Accelerate Nucleic Acid Amplification and CRISPR-Based Diagnostics. [PDF]

J Am Chem Soc
Homchan A, Patchsung M, Chantanakool P, Wongsatit T, Onchan W, Muengsaen D, Thaweeskulchai T, Tandean M, Sakpetch T, Suraritdechachai S, Aphicho K, Panchai C, Taiwan S, Horthongkham N, Sudyoadsuk T, Reinhardt A, Uttamapinant C.   +16 more
europepmc   +1 more source