Results 311 to 320 of about 205,585 (348)

Conformation of Viral Nucleic Acids in Situ

1969
Publisher Summary The problems that are discussed in this chapter are confined to viruses, and to be more exact, to the question of similarities and differences between the structure and properties of usual forms of nucleic acids in solution and that of nucleic acids inside viral particles.
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Conformational geometry and vibrational frequencies of nucleic acid chains

Biopolymers, 1975
AbstractNormal coordinate analysis of diethyl phosphate has been made, which predicts all observed Raman frequencies in the range 170–1300 cm−1. The force constants from this calculation have been transferred to a vibrational calculation for a simplified model of the backbone of nucleic acids, which also involves the OPO2−O phosphate group and the ...
E B, Brown, W L, Peticolas
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Triangulating Nucleic Acid Conformations Using Multicolor Surface Energy Transfer

ACS Nano, 2016
Optical ruler methods employing multiple fluorescent labels offer great potential for correlating distances among several sites, but are generally limited to interlabel distances under 10 nm and suffer from complications due to spectral overlap. Here we demonstrate a multicolor surface energy transfer (McSET) technique able to triangulate multiple ...
Ryan A, Riskowski, Rachel E, Armstrong, Nancy L, Greenbaum, Geoffrey F, Strouse   +3 more
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Watersoluble synthetic nucleic acid analogs--polyethyleneimine derivatives containing nucleic acid bases--conformation and interactionwith nucleic acids.

Nucleic acids symposium series, 1991
Water soluble polyethyleneimine derivatives containing nucleic acid bases were found to interact with polynucleotides, DNA, RNA. The conformational change by formation of complex was observed by CD spectra and was discussed with the hypochromicity in UV spectra.
T, Wada, E, Mochizuki, Y, Inaki, K, Takemoto   +3 more
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Alternative conformations of a nucleic acid four-way junction

Journal of Molecular Biology, 2000
A crystal structure of a 108 nucleotide RNA-DNA complex containing a four-way junction was solved at 3.1 A resolution. The structure of the junction differs substantially from the "stacked-X" conformation observed previously, due to a 135 degrees rotation of the branches.
J, Nowakowski, P J, Shim, C D, Stout, G F, Joyce   +3 more
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Computing Nonequilibrium Conformational Dynamics of Structured Nucleic Acid Assemblies

Journal of Chemical Theory and Computation, 2015
Synthetic nucleic acids can be programmed to form precise three-dimensional structures on the nanometer-scale. These thermodynamically stable complexes can serve as structural scaffolds to spatially organize functional molecules including multiple enzymes, chromophores, and force-sensing elements with internal dynamics that include substrate reaction ...
Reza Sharifi, Sedeh, Keyao, Pan, Matthew Ralph, Adendorff, Oskar, Hallatschek, Klaus-Jürgen, Bathe, Mark, Bathe   +5 more
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Theoretical Probes of Nucleic Acid Conformation

1983
The computations described briefly here illustrate the interrelationship between the local structure and macroscopic behavior of the DNA helix. Statistical mechanical studies help to identify the most likely morphological arrangements of the polynucleotide backbone and to understand the macroscopic flexibility of the DNA as a whole.
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Nucleic acid analogs: Conformation and their functionalities

Die Makromolekulare Chemie, 1985
Poly-L-, -D-, and -DL-lysine derivatives having pendant nucleic acid bases were prepared by using a polymer modification reaction. Conformation of the polymers was studied by CD and ORD measurements, and the effects of pH of the system, as well as the solvents on the helicity of the polymers were investigated in detail.
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Evolution of conformational principles in nucleic acids

International Journal of Quantum Chemistry, 2009
The analysis of conformations of nucleic acids and polynucleotides have been greatly simplified by the important observations that the nucleotide building blocks exhibit two classes of preferred conformations and that the flexibility in the polynucleotide chain resides mainly in the internucleotide PO linkages.
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Magnesium-nucleic acid conformational changes and cancer.

Magnesium, 1987
The magnesium interaction with the mononucleotide guanosine-5'-monophosphate disodium salt (5'-GMP Na2 or G5'p) has been studied by Fourier transform infrared spectroscopy. The results have been compared with previously obtained proton nuclear magnetic data on the same system as well as other similar systems.
T, Theophanides, M, Polissiou
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